Detailed information NTG0260931

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: CR921_RS04805
• Genome accession: NZ_CP025399
• Coordinates: 902467..903192 (+)
• Length: 241 a.a.
• NCBI ID: WP_101415611.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain GABA
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 897467..908192

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR921_RS04765	-	897560..897742 (+)	183	WP_006531883.1	Blp family class II bacteriocin	-
CR921_RS04775	-	898359..898589 (+)	231	WP_043878356.1	bacteriocin	-
CR921_RS04780	-	898678..898989 (+)	312	WP_003066586.1	hypothetical protein	-
CR921_RS04785	-	899203..899295 (+)	93	Protein_875	Blp family class II bacteriocin	-
CR921_RS04790	-	899353..899757 (+)	405	WP_015695682.1	hypothetical protein	-
CR921_RS04795	-	899938..900984 (+)	1047	WP_095559358.1	thioredoxin fold domain-containing protein	-
CR921_RS04800	-	901516..902280 (+)	765	WP_232086163.1	DUF6261 family protein	-
CR921_RS04805	comE/comE1	902467..903192 (+)	726	WP_101415611.1	LytR/AlgR family response regulator transcription factor	Regulator
CR921_RS04810	-	903205..904524 (+)	1320	WP_095559360.1	sensor histidine kinase	-
CR921_RS04815	-	904545..904694 (-)	150	WP_006531893.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
CR921_RS04825	-	905221..905805 (+)	585	WP_232086162.1	hypothetical protein	-
CR921_RS04830	csm6	905820..906911 (+)	1092	WP_101415612.1	type III-A CRISPR-associated CARF protein Csm6	-
CR921_RS04835	pyrF	907112..907807 (+)	696	WP_011681116.1	orotidine-5'-phosphate decarboxylase	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 28093.06 Da
• Isoelectric Point: 5.0805

>NTDB_id=260931 CR921_RS04805 WP_101415611.1 902467..903192(+) (comE/comE1) [Streptococcus thermophilus strain GABA]
MDIFVLEDDIPQQFRMERAINLVMESNNWHYRYLEISSNPDEIIAVAGNGEHQIFFLDLEIKGEEQQGIDVAKAIREKNS
TAIIVFVTTHSEFMLLTYQSLVGAIDFIDKGLNEEAFNERLFVCLKEAVKRQEGNFGEHSYLFHTPQAKVRVAYDDILFF
ETSPAPHRIILHTKNERTEFYATIAEVAKSDERLFRCHRSFVVNVDNIARFDMRYKLIYFEMGETCPVARAKVKLLQEKI
E

Nucleotide

• Length: 726 bp

>NTDB_id=260931 CR921_RS04805 WP_101415611.1 902467..903192(+) (comE/comE1) [Streptococcus thermophilus strain GABA]
GTGGATATTTTTGTACTCGAAGATGATATTCCCCAACAATTCCGAATGGAGCGTGCTATTAATCTTGTGATGGAATCAAA
TAACTGGCATTATCGGTATTTGGAGATTTCATCTAATCCTGATGAAATCATCGCAGTAGCAGGTAATGGTGAACATCAAA
TTTTCTTTCTTGATTTAGAAATTAAAGGTGAAGAGCAGCAAGGGATTGATGTTGCTAAAGCTATTCGTGAAAAAAATAGC
ACAGCTATTATTGTTTTTGTGACGACACATTCTGAATTCATGCTCTTAACCTATCAATCTTTAGTAGGTGCTATTGACTT
TATTGACAAAGGATTAAACGAAGAAGCGTTTAATGAACGCTTATTCGTTTGTCTTAAAGAAGCTGTCAAACGCCAAGAGG
GAAACTTTGGTGAACATTCCTACTTGTTTCATACCCCACAAGCCAAAGTGCGGGTAGCTTATGATGATATTTTATTTTTT
GAAACGTCACCAGCACCTCATCGTATTATTTTGCACACTAAGAACGAACGTACAGAATTTTATGCGACCATAGCAGAAGT
GGCAAAATCAGATGAACGTCTTTTTAGATGTCATCGTTCTTTTGTGGTTAACGTGGATAATATCGCTAGATTTGATATGA
GGTATAAGCTCATTTATTTTGAGATGGGAGAAACCTGTCCTGTAGCTAGGGCTAAGGTGAAATTATTACAGGAGAAAATT
GAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-120)

• LytTr DNA-binding domain (LytTR) (150-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	65.823	98.34	0.647
comE/blpR	Streptococcus mutans UA159	46.281	100	0.465
comE/comE2	Streptococcus equinus JB1	44.398	100	0.444
comE/comE2	Streptococcus gordonii strain NCTC7865	35.06	100	0.365
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	35.06	100	0.365
agrA	Staphylococcus aureus N315	35.656	100	0.361