Detailed information NTG0260913

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: CR921_RS01455
• Genome accession: NZ_CP025399
• Coordinates: 260061..260960 (+)
• Length: 299 a.a.
• NCBI ID: WP_011680720.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain GABA
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 255061..265960

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR921_RS01435	trkA	256198..257547 (-)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-
CR921_RS01440	-	257836..258345 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
CR921_RS01445	-	258656..259213 (+)	558	WP_011680718.1	ECF transporter S component	-
CR921_RS01450	-	259216..259866 (+)	651	WP_011680719.1	phosphatase PAP2 family protein	-
CR921_RS01455	comR	260061..260960 (+)	900	WP_011680720.1	helix-turn-helix domain-containing protein	Regulator
CR921_RS09875	-	261198..261779 (+)	582	Protein_234	cysteine peptidase family C39 domain-containing protein	-
CR921_RS09880	comA	261764..262054 (+)	291	WP_194238295.1	ABC transporter transmembrane domain-containing protein	Regulator
CR921_RS10175	comA	262397..262606 (+)	210	WP_002946147.1	hypothetical protein	Regulator
CR921_RS01475	-	262661..263229 (+)	569	Protein_237	ATP-binding cassette domain-containing protein	-
CR921_RS10180	-	263460..263648 (+)	189	WP_224103239.1	hypothetical protein	-
CR921_RS10185	-	263616..263900 (-)	285	WP_232557103.1	hypothetical protein	-
CR921_RS10190	-	264141..264443 (-)	303	WP_224103194.1	hypothetical protein	-
CR921_RS10195	-	264667..265038 (-)	372	WP_224103195.1	hypothetical protein	-
CR921_RS01490	-	265444..265959 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35271.71 Da
• Isoelectric Point: 5.1073

>NTDB_id=260913 CR921_RS01455 WP_011680720.1 260061..260960(+) (comR) [Streptococcus thermophilus strain GABA]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIVFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=260913 CR921_RS01455 WP_011680720.1 260061..260960(+) (comR) [Streptococcus thermophilus strain GABA]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTTTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAGTGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMD-9	100	100	1
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.472	100	0.415