Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   CWI26_RS08335 Genome accession   NZ_CP025043
Coordinates   1692439..1693143 (-) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain AH681     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1687439..1698143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS08315 (CWI26_08315) vga(F) 1688370..1689755 (-) 1386 WP_233486241.1 ABC-F type ribosomal protection protein Vga(F) -
  CWI26_RS08325 (CWI26_08325) vicX 1690287..1691090 (-) 804 WP_100881579.1 MBL fold metallo-hydrolase Regulator
  CWI26_RS08330 (CWI26_08330) micB 1691097..1692446 (-) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CWI26_RS08335 (CWI26_08335) micA 1692439..1693143 (-) 705 WP_004298854.1 response regulator YycF Regulator
  CWI26_RS08340 (CWI26_08340) - 1693337..1694098 (+) 762 WP_004298852.1 amino acid ABC transporter ATP-binding protein -
  CWI26_RS08345 (CWI26_08345) - 1694109..1694948 (+) 840 WP_100881580.1 transporter substrate-binding domain-containing protein -
  CWI26_RS08350 (CWI26_08350) - 1694963..1695661 (+) 699 WP_029185563.1 amino acid ABC transporter permease -
  CWI26_RS08355 (CWI26_08355) - 1695676..1696335 (+) 660 WP_029185562.1 amino acid ABC transporter permease -
  CWI26_RS12350 (CWI26_08360) - 1696458..1696751 (+) 294 WP_100881581.1 acyltransferase family protein -
  CWI26_RS08365 (CWI26_08365) - 1696715..1697509 (+) 795 WP_158293412.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=257618 CWI26_RS08335 WP_004298854.1 1692439..1693143(-) (micA) [Streptococcus suis strain AH681]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=257618 CWI26_RS08335 WP_004298854.1 1692439..1693143(-) (micA) [Streptococcus suis strain AH681]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAGATTGAAGATACAC
CAAGCCGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment