Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   CWI26_RS08330 Genome accession   NZ_CP025043
Coordinates   1691097..1692446 (-) Length   449 a.a.
NCBI ID   WP_024379730.1    Uniprot ID   A0A0Z8J8V5
Organism   Streptococcus suis strain AH681     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1686097..1697446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS08310 (CWI26_08310) pbp2b 1686206..1688278 (-) 2073 WP_024376693.1 penicillin-binding protein PBP2B -
  CWI26_RS08315 (CWI26_08315) vga(F) 1688370..1689755 (-) 1386 WP_233486241.1 ABC-F type ribosomal protection protein Vga(F) -
  CWI26_RS08325 (CWI26_08325) vicX 1690287..1691090 (-) 804 WP_100881579.1 MBL fold metallo-hydrolase Regulator
  CWI26_RS08330 (CWI26_08330) micB 1691097..1692446 (-) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CWI26_RS08335 (CWI26_08335) micA 1692439..1693143 (-) 705 WP_004298854.1 response regulator YycF Regulator
  CWI26_RS08340 (CWI26_08340) - 1693337..1694098 (+) 762 WP_004298852.1 amino acid ABC transporter ATP-binding protein -
  CWI26_RS08345 (CWI26_08345) - 1694109..1694948 (+) 840 WP_100881580.1 transporter substrate-binding domain-containing protein -
  CWI26_RS08350 (CWI26_08350) - 1694963..1695661 (+) 699 WP_029185563.1 amino acid ABC transporter permease -
  CWI26_RS08355 (CWI26_08355) - 1695676..1696335 (+) 660 WP_029185562.1 amino acid ABC transporter permease -
  CWI26_RS12350 (CWI26_08360) - 1696458..1696751 (+) 294 WP_100881581.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51035.09 Da        Isoelectric Point: 4.5202

>NTDB_id=257617 CWI26_RS08330 WP_024379730.1 1691097..1692446(-) (micB) [Streptococcus suis strain AH681]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=257617 CWI26_RS08330 WP_024379730.1 1691097..1692446(-) (micB) [Streptococcus suis strain AH681]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCTAATTCCCTCAATGATTTGTCCGAG
GTTATCCGCTTAACTCACGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACAATTCGTAGTGAGAGTGG
TCTGATTTCTGGTTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCCTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCACGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTGGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8J8V5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment