Detailed information NTG0257616

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DLM82_RS10495
• Genome accession: NZ_CP029749
• Coordinates: 2000172..2002748 (-)
• Length: 858 a.a.
• NCBI ID: WP_001118379.1
• Uniprot ID: Q3JYM3
• Organism: Streptococcus agalactiae strain PLGBS13
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1995172..2007748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DLM82_RS10465 (DLM82_10450)	-	1995283..1995834 (-)	552	WP_000817341.1	DNA-3-methyladenine glycosylase I	-
DLM82_RS10470 (DLM82_10455)	ruvA	1995857..1996447 (-)	591	WP_000272490.1	Holliday junction branch migration protein RuvA	Machinery gene
DLM82_RS10475 (DLM82_10460)	-	1996449..1997681 (-)	1233	WP_000657472.1	MFS transporter	-
DLM82_RS10480 (DLM82_10465)	hexB	1997713..1999686 (-)	1974	WP_000034614.1	DNA mismatch repair endonuclease MutL	Machinery gene
DLM82_RS10490 (DLM82_10475)	-	1999912..2000115 (+)	204	WP_000191849.1	cold-shock protein	-
DLM82_RS10495 (DLM82_10480)	hexA	2000172..2002748 (-)	2577	WP_001118379.1	DNA mismatch repair protein MutS	Machinery gene
DLM82_RS10500 (DLM82_10485)	argR	2002805..2003242 (-)	438	WP_001033152.1	arginine repressor	-
DLM82_RS10505 (DLM82_10490)	argS	2003464..2005155 (+)	1692	WP_000379864.1	arginine--tRNA ligase	-
DLM82_RS10510 (DLM82_10495)	-	2005243..2005551 (+)	309	WP_001138859.1	bacteriocin immunity protein	-
DLM82_RS10515 (DLM82_10500)	-	2005578..2006450 (-)	873	WP_000915478.1	YitT family protein	-
DLM82_RS10520 (DLM82_10505)	-	2006558..2007502 (-)	945	WP_000857770.1	YitT family protein	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 96991.56 Da
• Isoelectric Point: 4.8181

>NTDB_id=257616 DLM82_RS10495 WP_001118379.1 2000172..2002748(-) (hexA) [Streptococcus agalactiae strain PLGBS13]
MAKPTISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAEKPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKKAVGVVKREVVQVVTPGTVVESTKPDSANNFLVAIDSQDQQTFGLAYMDVSTGEFQATLLTDFE
SVRSEILNLKAREIVVGYQLTDEKNHLLTKQMNLLLSYEDERLNDIHLIDEQLTDLEISAAEKLLQYVHRTQKRELSHLQ
KVVHYEIKDYLQMSYATKNSLDLLENARTSKKHGSLYWLLDETKTAMGTRMLRTWIDRPLVSMNRIKERQDIIQVFLDYF
FERNDLTESLKGVYDIERLASRVSFGKANPKDLLQLGQTLSQIPRIKMILQSFNQPELDIVVNKIDTMPELESLINTAIA
PEAQATITEGNIIKSGFDKQLDNYRTVMREGTGWIADIEAKERAASGIGTLKIDYNKKDGYYFHVTNSNLSLVPEHFFRK
ATLKNSERYGTAELAKIEGEVLEAREQSSNLEYDIFMRVRAQVESYIKRLQELAKTIATVDVLQSLAVVAENHHYVRPKF
NDEHQIKIKNGRHATVEKVMGVQEYIPNSIYFDSQTDIQLITGPNMSGKSTYMRQLALTVIMAQMGGFVSADEVDLPVFD
AIFTRIGAADDLISGQSTFMVEMMEANQAVKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHDRVRAKTMFATHYHE
LTDLSEQLTRLVNVHVATLERDGEVTFLHKIESGPADKSYGIHVAKIAGLPIDLLDRATDILSQLEADAVQLIVSAPQEA
VTADLNEELDSEKQQGQLSLFEEPSNAGRVIEELEAIDIMNLTPMQAMNAIFDLKKLL

Nucleotide

• Length: 2577 bp

>NTDB_id=257616 DLM82_RS10495 WP_001118379.1 2000172..2002748(-) (hexA) [Streptococcus agalactiae strain PLGBS13]
ATGGCCAAGCCAACGATATCACCGGGAATGCAACAGTATCTGGATATAAAAGAGAATTATCCAGATGCTTTTTTGCTTTT
TAGAATGGGTGATTTTTATGAATTATTTTATGATGATGCGGTAAAAGCAGCACAAATCCTGGAGATTAGCTTGACTAGTC
GAAATAAGAACGCAGAAAAGCCAATCCCAATGGCAGGTGTTCCCTATCACTCAGCTCAACAGTATATTGACGTTTTAGTT
GAATTAGGTTACAAAGTAGCCATTGCTGAGCAGATGGAAGATCCTAAAAAAGCTGTGGGAGTGGTAAAGCGTGAGGTAGT
GCAAGTTGTTACCCCAGGAACGGTTGTGGAGTCAACGAAGCCGGATAGTGCTAATAATTTCTTAGTAGCGATTGATTCGC
AAGATCAACAAACATTTGGTCTAGCATATATGGATGTCTCAACTGGAGAGTTTCAGGCAACCCTTTTAACAGATTTTGAG
TCCGTCCGTAGTGAAATACTAAATTTAAAAGCTCGTGAGATTGTAGTAGGATATCAATTGACGGACGAAAAAAATCACCT
ACTGACGAAGCAGATGAACTTGCTTTTATCATACGAAGACGAACGACTTAATGATATTCATTTGATTGATGAACAGTTAA
CTGATTTGGAAATATCTGCTGCGGAAAAACTTTTACAATATGTGCATAGAACACAAAAGCGTGAACTTAGTCATTTACAG
AAAGTAGTTCATTATGAAATAAAGGACTATTTACAAATGTCATATGCAACGAAAAATAGTCTAGATTTACTGGAGAATGC
TAGAACAAGCAAGAAGCACGGAAGTCTTTACTGGTTGTTAGATGAGACTAAAACAGCGATGGGAACTCGAATGCTGAGAA
CTTGGATTGACAGGCCTTTGGTAAGTATGAATCGAATCAAGGAACGTCAAGATATTATTCAAGTGTTTCTTGATTATTTT
TTTGAGAGAAACGATCTCACAGAAAGTTTAAAGGGTGTATATGATATTGAACGTCTAGCAAGTCGAGTATCTTTCGGAAA
AGCCAACCCTAAAGATCTATTGCAACTCGGACAGACCTTATCACAAATTCCTCGGATTAAAATGATTTTACAGTCCTTCA
ATCAACCTGAGCTTGACATTGTTGTCAACAAAATTGACACTATGCCTGAATTAGAAAGTTTAATTAATACGGCGATAGCC
CCAGAAGCACAGGCTACTATCACTGAGGGAAACATTATCAAGTCTGGATTTGATAAGCAATTGGATAATTATCGAACAGT
GATGCGTGAAGGTACAGGTTGGATTGCTGATATTGAAGCTAAGGAAAGAGCAGCAAGTGGTATCGGTACTCTTAAAATTG
ATTATAATAAAAAAGACGGTTATTACTTCCATGTTACCAATTCCAATTTATCACTAGTACCGGAGCATTTTTTCCGTAAA
GCGACGTTAAAAAATTCTGAACGCTATGGAACAGCAGAACTAGCCAAAATTGAAGGTGAAGTGCTCGAAGCTCGCGAGCA
ATCTTCAAATTTAGAATATGATATTTTTATGCGTGTTCGTGCTCAAGTAGAATCTTATATTAAACGTCTTCAAGAGCTAG
CAAAGACTATTGCAACCGTTGATGTTCTACAGAGTTTGGCAGTAGTTGCAGAAAATCATCACTATGTTCGTCCCAAATTT
AATGATGAACATCAGATTAAGATTAAGAATGGGCGTCATGCAACCGTTGAAAAAGTGATGGGAGTGCAAGAATATATTCC
CAATAGTATCTATTTTGATAGTCAGACAGATATCCAGTTGATTACAGGACCAAATATGAGTGGTAAGTCGACCTATATGC
GCCAGTTAGCTTTGACAGTTATTATGGCACAAATGGGAGGTTTTGTATCGGCAGACGAAGTTGATTTGCCTGTATTTGAT
GCAATATTTACTAGGATTGGTGCTGCTGATGACTTAATTTCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCGAA
TCAGGCTGTAAAACGAGCCAGTGATAAATCTTTGATTCTTTTTGATGAATTAGGTCGAGGGACAGCCACTTATGATGGTA
TGGCATTAGCTCAATCGATTATAGAATATATTCATGACCGTGTTAGGGCAAAAACAATGTTTGCAACTCATTACCATGAG
TTGACAGATTTATCTGAACAATTGACAAGGCTTGTCAATGTACACGTGGCTACTTTAGAGAGAGATGGAGAAGTTACCTT
CTTACATAAAATTGAATCTGGACCTGCGGATAAGTCTTATGGGATACACGTCGCAAAAATAGCTGGTTTACCAATTGACT
TATTGGATAGGGCAACTGATATTTTATCACAGTTGGAAGCTGATGCAGTACAGTTGATCGTATCAGCCCCCCAAGAAGCT
GTTACTGCTGACTTAAATGAGGAACTAGATTCTGAGAAGCAACAAGGACAATTATCACTTTTTGAAGAACCTTCAAATGC
AGGTAGGGTTATTGAGGAGTTAGAAGCGATAGATATAATGAATCTAACTCCAATGCAAGCTATGAATGCTATATTTGACT
TAAAGAAATTATTATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (257-547)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (600-786)

• MutS domain II (MutS_II) (126-240)

• MutS family domain IV (MutS_IV) (416-506)

3D structure

• AlphaFold DB: Q3JYM3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	68.998	100	0.69
mutS	Pseudomonas stutzeri strain ATCC 17587	36.209	100	0.372