Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   CVO91_RS03535 Genome accession   NZ_CP024974
Coordinates   650752..651456 (+) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain CZ130302     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 645752..656456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS03510 (CVO91_03510) - 646394..647437 (-) 1044 WP_100664759.1 acyltransferase -
  CVO91_RS03515 (CVO91_03515) - 647560..648219 (-) 660 WP_004298846.1 amino acid ABC transporter permease -
  CVO91_RS03520 (CVO91_03520) - 648234..648932 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  CVO91_RS03525 (CVO91_03525) - 648947..649786 (-) 840 WP_004298850.1 transporter substrate-binding domain-containing protein -
  CVO91_RS03530 (CVO91_03530) - 649797..650558 (-) 762 WP_004298852.1 amino acid ABC transporter ATP-binding protein -
  CVO91_RS03535 (CVO91_03535) micA 650752..651456 (+) 705 WP_004298854.1 response regulator YycF Regulator
  CVO91_RS03540 (CVO91_03540) micB 651449..652798 (+) 1350 WP_004298856.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CVO91_RS03545 (CVO91_03545) vicX 652805..653608 (+) 804 WP_004298858.1 MBL fold metallo-hydrolase Regulator
  CVO91_RS03550 (CVO91_03550) vga(F) 653866..655251 (+) 1386 WP_004298859.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=256921 CVO91_RS03535 WP_004298854.1 650752..651456(+) (micA) [Streptococcus suis strain CZ130302]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=256921 CVO91_RS03535 WP_004298854.1 650752..651456(+) (micA) [Streptococcus suis strain CZ130302]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAGATTGAAGATACAC
CAAGCCGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment