Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   CVO91_RS03540 Genome accession   NZ_CP024974
Coordinates   651449..652798 (+) Length   449 a.a.
NCBI ID   WP_004298856.1    Uniprot ID   A0A2I5KE33
Organism   Streptococcus suis strain CZ130302     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 646449..657798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS03515 (CVO91_03515) - 647560..648219 (-) 660 WP_004298846.1 amino acid ABC transporter permease -
  CVO91_RS03520 (CVO91_03520) - 648234..648932 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  CVO91_RS03525 (CVO91_03525) - 648947..649786 (-) 840 WP_004298850.1 transporter substrate-binding domain-containing protein -
  CVO91_RS03530 (CVO91_03530) - 649797..650558 (-) 762 WP_004298852.1 amino acid ABC transporter ATP-binding protein -
  CVO91_RS03535 (CVO91_03535) micA 650752..651456 (+) 705 WP_004298854.1 response regulator YycF Regulator
  CVO91_RS03540 (CVO91_03540) micB 651449..652798 (+) 1350 WP_004298856.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CVO91_RS03545 (CVO91_03545) vicX 652805..653608 (+) 804 WP_004298858.1 MBL fold metallo-hydrolase Regulator
  CVO91_RS03550 (CVO91_03550) vga(F) 653866..655251 (+) 1386 WP_004298859.1 ABC-F type ribosomal protection protein Vga(F) -
  CVO91_RS03555 (CVO91_03555) pbp2b 655343..657415 (+) 2073 WP_004298861.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51123.17 Da        Isoelectric Point: 4.5294

>NTDB_id=256922 CVO91_RS03540 WP_004298856.1 651449..652798(+) (micB) [Streptococcus suis strain CZ130302]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGEMDVELINFTAFVTFILNRFDQMKHSDSDKVYTIVRDYQISPIW
VEIDTDKLTQVLDNILNNAVKYSPDGGTITFSMKTTDSQLIVSISDEGLGIPKADLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSRDITMDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=256922 CVO91_RS03540 WP_004298856.1 651449..652798(+) (micB) [Streptococcus suis strain CZ130302]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAGGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCCCTCAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGATTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCCTAGATGAGACCAACCGCATGATGCGGATGATTACTGATTTGTTAAG
TTTGTCAAGGATTGATAATCAAGTCGGTGAAATGGATGTTGAATTGATTAACTTTACAGCCTTTGTGACCTTTATTCTCA
ACCGTTTTGATCAGATGAAGCATTCTGATTCCGATAAAGTTTATACCATTGTTCGTGATTATCAAATAAGTCCAATCTGG
GTAGAAATTGATACAGATAAGCTGACCCAAGTTTTGGATAATATCTTAAACAATGCCGTCAAGTATTCACCTGACGGTGG
GACTATTACCTTTAGTATGAAAACGACAGATAGTCAGTTGATTGTTTCAATTTCGGATGAGGGCTTGGGGATTCCAAAGG
CTGATTTACCAAAGATTTTCGACCGATTCTATCGTGTAGATAAGGCTCGTTCGCGTGCCCAAGGTGGCACTGGTCTAGGT
TTGGCCATTGCCAAAGAAATTGTCAAGCAACACAAGGGATTCATTTGGGCCAAGAGTGAGTATGGTCATGGGTCAACGTT
TACGATTGTTCTACCGTACAGTAGGGACATTACTATGGATGAGTGGGATGATTCGGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I5KE33

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.495

97.105

0.675
  vicK Streptococcus mutans UA159

70.471

89.755

0.633

Multiple sequence alignment