Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   CVO91_RS02885 Genome accession   NZ_CP024974
Coordinates   528874..530166 (+) Length   430 a.a.
NCBI ID   WP_004195177.1    Uniprot ID   A0A0Z8H0V1
Organism   Streptococcus suis strain CZ130302     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 523874..535166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS02850 (CVO91_02850) - 525288..525713 (+) 426 WP_004195047.1 DUF1366 domain-containing protein -
  CVO91_RS02855 (CVO91_02855) - 525717..525929 (+) 213 WP_004195045.1 hypothetical protein -
  CVO91_RS02860 (CVO91_02860) - 525933..526358 (+) 426 WP_004195044.1 hypothetical protein -
  CVO91_RS02865 (CVO91_02865) - 526362..526616 (+) 255 WP_004195043.1 phage holin -
  CVO91_RS02870 (CVO91_02870) - 526703..527389 (+) 687 WP_004195041.1 CHAP domain-containing protein -
  CVO91_RS02875 (CVO91_02875) - 527450..527827 (+) 378 WP_004195039.1 PBECR2 nuclease fold domain-containing protein -
  CVO91_RS02880 (CVO91_02880) - 528185..528817 (-) 633 WP_004195179.1 YigZ family protein -
  CVO91_RS02885 (CVO91_02885) comFA/cflA 528874..530166 (+) 1293 WP_004195177.1 DEAD/DEAH box helicase Machinery gene
  CVO91_RS02890 (CVO91_02890) comFC/cflB 530159..530824 (+) 666 WP_002941737.1 ComF family protein Machinery gene
  CVO91_RS02895 (CVO91_02895) raiA 530902..531444 (+) 543 WP_002941735.1 ribosome-associated translation inhibitor RaiA -
  CVO91_RS02900 (CVO91_02900) tnpA 531605..532111 (+) 507 Protein_527 IS200/IS605 family transposase -
  CVO91_RS02905 (CVO91_02905) - 532353..533483 (+) 1131 WP_100664749.1 ISAs1 family transposase -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48947.43 Da        Isoelectric Point: 8.8921

>NTDB_id=256918 CVO91_RS02885 WP_004195177.1 528874..530166(+) (comFA/cflA) [Streptococcus suis strain CZ130302]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYQAADNAVKEDGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTSSSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=256918 CVO91_RS02885 WP_004195177.1 528874..530166(+) (comFA/cflA) [Streptococcus suis strain CZ130302]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTGCGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAATGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTGTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCAAGCAGCAGATAATGCGGTCAAGGAAGACGGAGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAATCCGCTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCAGGCTTTCCCTTACTTATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCTAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACATCATCCAGTCTAGTGCAGATTGCAGGTCGGGTTGGTAGGAGTATGGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8H0V1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.285

100

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae D39

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae R6

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae TIGR4

66.589

100

0.667
  comFA/cflA Streptococcus mitis SK321

66.125

100

0.663
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.326

0.5
  comFA Latilactobacillus sakei subsp. sakei 23K

38.051

100

0.381
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363

Multiple sequence alignment