Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   CUC43_RS22765 Genome accession   NZ_CP024771
Coordinates   4265748..4266329 (+) Length   193 a.a.
NCBI ID   WP_000991609.1    Uniprot ID   A0A853X8N5
Organism   Bacillus thuringiensis LM1212     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4260748..4271329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CUC43_RS22740 (CUC43_23530) - 4261862..4263229 (+) 1368 WP_029438608.1 lytic polysaccharide monooxygenase -
  CUC43_RS22745 (CUC43_23535) - 4263360..4263794 (-) 435 WP_029438607.1 GNAT family N-acetyltransferase -
  CUC43_RS22750 (CUC43_23540) rpiA 4263909..4264571 (-) 663 WP_029438606.1 ribose 5-phosphate isomerase A -
  CUC43_RS22755 (CUC43_23545) - 4264576..4264896 (-) 321 WP_029438605.1 2Fe-2S iron-sulfur cluster-binding protein -
  CUC43_RS22760 (CUC43_23550) - 4265040..4265726 (+) 687 WP_029438604.1 RNA polymerase subunit sigma-70 -
  CUC43_RS22765 (CUC43_23555) clpP 4265748..4266329 (+) 582 WP_000991609.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  CUC43_RS22770 (CUC43_23560) - 4266376..4267233 (-) 858 WP_029438603.1 glycine betaine ABC transporter substrate-binding protein -
  CUC43_RS22775 (CUC43_23565) - 4267405..4268610 (+) 1206 WP_029438602.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  CUC43_RS22780 (CUC43_23570) - 4268603..4269439 (+) 837 WP_029438601.1 proline/glycine betaine ABC transporter permease -
  CUC43_RS22785 - 4269490..4269726 (-) 237 WP_029438600.1 hypothetical protein -
  CUC43_RS22790 (CUC43_23580) - 4269944..4270108 (+) 165 WP_029438599.1 hypothetical protein -
  CUC43_RS22795 (CUC43_23585) - 4270209..4270700 (+) 492 WP_061686514.1 HIT family protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21192.49 Da        Isoelectric Point: 5.3394

>NTDB_id=255382 CUC43_RS22765 WP_000991609.1 4265748..4266329(+) (clpP) [Bacillus thuringiensis LM1212]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=255382 CUC43_RS22765 WP_000991609.1 4265748..4266329(+) (clpP) [Bacillus thuringiensis LM1212]
ATGAATGCAATTCCATATGTTGTAGAACAAACAAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
CCGTATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCCGGCGGATCAACGACAGCGGGATTTGCTATATTAGATACA
ATGAATTTAATCAAACCTGATGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCAAAAGGGCAAGCAA
CAGAAATTGAAATAACAGCAAAAAGGATATTAAAGTTAAAGCATGATATTAATAAAATGATTGCAGAAAAAACGGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACCGCAGAAGAAGCAAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A853X8N5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.196

97.927

0.658
  clpP Streptococcus pyogenes JRS4

56.085

97.927

0.549
  clpP Streptococcus pyogenes MGAS315

56.085

97.927

0.549
  clpP Streptococcus pneumoniae R6

55.208

99.482

0.549
  clpP Streptococcus pneumoniae TIGR4

55.208

99.482

0.549
  clpP Streptococcus pneumoniae Rx1

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMG 18311

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMD-9

55.208

99.482

0.549
  clpP Streptococcus pneumoniae D39

55.208

99.482

0.549
  clpP Streptococcus mutans UA159

53.968

97.927

0.528
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

50.265

97.927

0.492

Multiple sequence alignment