Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   DLJ51_RS00895 Genome accession   NZ_CP029560
Coordinates   153703..154746 (+) Length   347 a.a.
NCBI ID   WP_002959504.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NIDR 6715-7     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 148703..159746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ51_RS00875 (DLJ51_00875) - 148711..149073 (-) 363 WP_002959493.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  DLJ51_RS00880 (DLJ51_00880) - 149434..151818 (-) 2385 WP_019785320.1 HAD-IC family P-type ATPase -
  DLJ51_RS00885 (DLJ51_00885) - 152038..152406 (+) 369 WP_019781971.1 DUF1033 family protein -
  DLJ51_RS00890 (DLJ51_00890) comGA/cglA 152832..153779 (+) 948 WP_019777327.1 competence type IV pilus ATPase ComGA Machinery gene
  DLJ51_RS00895 (DLJ51_00895) comGB 153703..154746 (+) 1044 WP_002959504.1 competence type IV pilus assembly protein ComGB Machinery gene
  DLJ51_RS00900 (DLJ51_00900) comGC 154743..155069 (+) 327 WP_019770073.1 competence type IV pilus major pilin ComGC Machinery gene
  DLJ51_RS00905 (DLJ51_00905) comGD 155023..155457 (+) 435 WP_254051091.1 competence type IV pilus minor pilin ComGD Machinery gene
  DLJ51_RS00910 (DLJ51_00910) comGE 155429..155722 (+) 294 WP_002959510.1 competence type IV pilus minor pilin ComGE Machinery gene
  DLJ51_RS00915 (DLJ51_00915) comGF 155706..156143 (+) 438 WP_019781940.1 competence type IV pilus minor pilin ComGF Machinery gene
  DLJ51_RS00920 (DLJ51_00920) comGG 156121..156582 (+) 462 WP_019785527.1 competence type IV pilus minor pilin ComGG Machinery gene
  DLJ51_RS00930 (DLJ51_00930) - 156784..157050 (+) 267 WP_002959516.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DLJ51_RS00935 (DLJ51_00935) - 157037..157312 (+) 276 WP_109982370.1 helix-turn-helix domain-containing protein -
  DLJ51_RS00940 (DLJ51_00940) comGH 157411..158364 (+) 954 WP_019771347.1 class I SAM-dependent methyltransferase Machinery gene
  DLJ51_RS00945 (DLJ51_00945) - 158427..159623 (+) 1197 WP_019771614.1 acetate kinase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40128.76 Da        Isoelectric Point: 10.1589

>NTDB_id=254159 DLJ51_RS00895 WP_002959504.1 153703..154746(+) (comGB) [Streptococcus sobrinus strain NIDR 6715-7]
MKKLTNFLQQDISLRKRRPPKKLKTSRQRKVIQLFNNLLESGFTLTEIVDFLDRSSLLAPAYTKEMRASLLAGENLAAMM
GKLGFSDDVVTQLSLAELHGNTQGSLLKIEAYLAHLMTVKRKLWEVATYPIILLTFLILIMLGLRNYLLPQLERTNLATR
IINHFPLVFLIGVLVLALVILCLIWLQRRSRKITWYSRLARLPLLGRFVQLYLTAYYAREWGNLIGQGVEMSRIVQLMQE
QRSQLFQEIGREMEAALLAGQEFHHKVLDYPFFLRELSLIIEYGQVKSKLGSELEVYAQETWEAFFSRVNRATQLIQPLV
FILVALVIVMIYAAMLLPMYHNMEVPL

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=254159 DLJ51_RS00895 WP_002959504.1 153703..154746(+) (comGB) [Streptococcus sobrinus strain NIDR 6715-7]
ATGAAAAAATTGACCAACTTCTTGCAGCAGGACATCTCACTGAGGAAGAGGCGGCCGCCGAAAAAATTAAAGACTAGCCG
GCAGCGTAAGGTCATCCAACTCTTCAATAATCTTCTGGAGTCGGGCTTTACCCTAACCGAGATTGTGGATTTTCTGGACC
GCAGTAGCCTTCTGGCTCCGGCCTATACCAAGGAGATGCGGGCCTCCCTCTTGGCGGGGGAAAATTTGGCAGCTATGATG
GGCAAGTTAGGCTTTTCCGATGATGTGGTCACTCAGCTTTCTCTGGCAGAACTGCATGGCAATACCCAAGGCAGTCTCCT
GAAAATCGAGGCTTATCTAGCCCACCTCATGACTGTCAAAAGGAAGCTTTGGGAGGTCGCTACCTATCCCATTATTCTTC
TAACCTTTTTGATTCTGATTATGCTGGGCCTGCGAAATTATCTCTTACCCCAGTTGGAAAGGACCAACCTGGCGACCAGG
ATAATCAATCATTTTCCTCTGGTCTTTCTAATTGGAGTACTGGTTTTGGCCTTAGTCATTCTTTGCTTGATCTGGTTACA
AAGACGGTCGCGAAAAATCACCTGGTACAGCCGCCTGGCTAGACTCCCTTTGCTGGGAAGATTTGTCCAACTCTACTTGA
CTGCCTATTATGCTAGGGAGTGGGGCAATTTGATTGGTCAGGGGGTAGAAATGAGCCGGATTGTCCAACTTATGCAAGAG
CAAAGATCCCAACTCTTCCAGGAGATTGGCCGAGAGATGGAGGCGGCTCTTCTAGCTGGTCAAGAATTCCACCACAAGGT
TTTGGACTATCCCTTCTTCCTTCGGGAATTGAGCCTGATTATTGAATATGGTCAGGTCAAATCTAAATTAGGTAGTGAGC
TGGAGGTCTATGCTCAGGAGACCTGGGAGGCCTTCTTTAGTCGGGTCAATCGAGCTACTCAGTTGATTCAGCCCTTAGTC
TTTATTCTGGTGGCCCTTGTTATCGTCATGATTTACGCAGCCATGTTGCTGCCCATGTATCACAATATGGAGGTACCTTT
ATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(32-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus mutans UA159

66.082

98.559

0.651
  comGB Streptococcus mutans UA140

65.789

98.559

0.648
  comGB Streptococcus gordonii str. Challis substr. CH1

61.628

99.135

0.611
  comGB/cglB Streptococcus mitis NCTC 12261

60.597

96.542

0.585
  comGB/cglB Streptococcus mitis SK321

59.701

96.542

0.576
  comGB/cglB Streptococcus pneumoniae Rx1

59.104

96.542

0.571
  comGB/cglB Streptococcus pneumoniae D39

59.104

96.542

0.571
  comGB/cglB Streptococcus pneumoniae R6

59.104

96.542

0.571
  comGB/cglB Streptococcus pneumoniae TIGR4

59.104

96.542

0.571
  comGB Lactococcus lactis subsp. cremoris KW2

51.032

97.695

0.499

Multiple sequence alignment