Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   DI496_RS11370 Genome accession   NZ_CP029369
Coordinates   1905890..1906546 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain WCHEC035148     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1900890..1911546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DI496_RS11345 (DI496_11345) dcyD 1901770..1902756 (+) 987 WP_046659907.1 D-cysteine desulfhydrase -
  DI496_RS11350 (DI496_11350) tcyL 1902771..1903439 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  DI496_RS11355 (DI496_11355) tcyN 1903436..1904188 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  DI496_RS11360 (DI496_11360) sdiA 1904418..1905140 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  DI496_RS11365 (DI496_11365) yecF 1905207..1905431 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  DI496_RS25980 yecU 1905418..1905594 (-) 177 WP_000590347.1 protein YecU -
  DI496_RS26820 - 1905677..1905748 (-) 72 Protein_1788 transcriptional regulator -
  DI496_RS11370 (DI496_11370) letA 1905890..1906546 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  DI496_RS11375 (DI496_11375) uvrC 1906543..1908375 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  DI496_RS11380 (DI496_11380) pgsA 1908432..1908980 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  DI496_RS11400 (DI496_11400) yecA 1909630..1910295 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=252993 DI496_RS11370 WP_000611335.1 1905890..1906546(+) (letA) [Escherichia coli strain WCHEC035148]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=252993 DI496_RS11370 WP_000611335.1 1905890..1906546(+) (letA) [Escherichia coli strain WCHEC035148]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment