Detailed information NTG0252376

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: DEH18_RS26715
• Genome accession: NZ_CP029241
• Coordinates: 6754289..6754972 (-)
• Length: 227 a.a.
• NCBI ID: WP_030885537.1
• Uniprot ID: -
• Organism: Streptomyces sp. NHF165
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 6749289..6759972

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DEH18_RS26685 (DEH18_27075)	-	6749412..6749792 (-)	381	WP_078873651.1	DUF3817 domain-containing protein	-
DEH18_RS26690 (DEH18_27080)	-	6749887..6750531 (+)	645	WP_030885552.1	AIM24 family protein	-
DEH18_RS26695 (DEH18_27085)	-	6750531..6751181 (+)	651	WP_030885549.1	AIM24 family protein	-
DEH18_RS26700 (DEH18_27090)	-	6751196..6751891 (+)	696	WP_037851298.1	AIM24 family protein	-
DEH18_RS26705 (DEH18_27095)	-	6752148..6752624 (+)	477	WP_030885543.1	MarR family transcriptional regulator	-
DEH18_RS26710 (DEH18_27100)	-	6752710..6754296 (-)	1587	WP_159788705.1	HAMP domain-containing sensor histidine kinase	-
DEH18_RS26715 (DEH18_27105)	ciaR	6754289..6754972 (-)	684	WP_030885537.1	response regulator transcription factor	Regulator
DEH18_RS26720 (DEH18_27110)	-	6755097..6755813 (+)	717	WP_086816978.1	PepSY domain-containing protein	-
DEH18_RS26725 (DEH18_27115)	meaB	6755995..6756987 (-)	993	WP_159788707.1	methylmalonyl Co-A mutase-associated GTPase MeaB	-
DEH18_RS26730 (DEH18_27120)	-	6757089..6758297 (-)	1209	WP_149562033.1	acetyl-CoA C-acetyltransferase	-
DEH18_RS26735 (DEH18_27125)	mce	6758445..6758888 (+)	444	WP_030885525.1	methylmalonyl-CoA epimerase	-

Sequence

Protein

• Length: 227 a.a.
• Molecular weight: 24675.17 Da
• Isoelectric Point: 4.7140

>NTDB_id=252376 DEH18_RS26715 WP_030885537.1 6754289..6754972(-) (ciaR) [Streptomyces sp. NHF165]
MRLLIVEDERRLALSLAKGLTAEGFAVDVVHDGAEGLHQATENDYDLIVLDIMLPGMNGYRVCAALRAAGDETPVLMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLLARIRALLRRRTRGAQPVLRIGALTVEPAVRRVTVGEDAADEVELTAKEFAV
LEYLAGRAGEVVSKSEILAHVWDFAYEGDANIVEVYISALRRKLGAGWIVTVRGAGYRLTDAGRGRA

Nucleotide

• Length: 684 bp

>NTDB_id=252376 DEH18_RS26715 WP_030885537.1 6754289..6754972(-) (ciaR) [Streptomyces sp. NHF165]
ATGCGCCTGCTGATCGTGGAGGACGAGCGCCGGCTGGCCCTGTCGCTCGCCAAGGGCCTGACGGCCGAGGGCTTCGCCGT
GGATGTCGTGCACGACGGTGCCGAAGGGCTCCACCAGGCGACCGAGAACGACTACGACTTGATCGTTCTCGACATCATGC
TGCCGGGGATGAACGGCTACCGGGTCTGCGCGGCGCTGCGGGCCGCCGGCGACGAGACGCCGGTGCTGATGCTCACCGCG
AAGGACGGCGAGTACGACGAGGCCGAGGGCCTGGACACCGGGGCCGACGACTACCTCACCAAGCCGTTCTCCTATGTCGT
CCTCCTCGCCCGGATCCGTGCGTTGCTGCGCCGCCGCACCCGCGGGGCGCAGCCCGTGCTGCGGATCGGCGCCCTCACCG
TGGAGCCCGCCGTGCGCCGGGTGACGGTCGGCGAGGACGCGGCGGACGAAGTGGAGCTGACCGCCAAGGAGTTCGCGGTC
CTGGAGTACCTCGCGGGCCGCGCCGGCGAGGTCGTCTCCAAGTCGGAGATCCTCGCGCACGTCTGGGACTTCGCCTACGA
GGGCGACGCCAACATCGTCGAGGTGTACATCAGCGCGCTGCGCCGCAAGCTGGGGGCCGGCTGGATCGTCACCGTGCGCG
GTGCCGGCTACCGCCTGACGGACGCGGGGCGCGGCCGTGCGTAG

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (149-219)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	42.105	100	0.423
ciaR	Streptococcus pneumoniae R6	40.529	100	0.405
ciaR	Streptococcus pneumoniae TIGR4	40.529	100	0.405
ciaR	Streptococcus pneumoniae Rx1	40.529	100	0.405
ciaR	Streptococcus pneumoniae D39	40.529	100	0.405
covR	Streptococcus salivarius strain HSISS4	40.889	99.119	0.405
covR	Lactococcus lactis subsp. lactis strain DGCC12653	40.444	99.119	0.401
vicR	Streptococcus mutans UA159	37.339	100	0.383
micA	Streptococcus pneumoniae Cp1015	36.91	100	0.379