Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   CG483_RS20540 Genome accession   NZ_CP024098
Coordinates   3894792..3895373 (+) Length   193 a.a.
NCBI ID   WP_012096148.1    Uniprot ID   A7GUT3
Organism   Bacillus cytotoxicus strain CH_38     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 3884553..3895373 3894792..3895373 within 0


Gene organization within MGE regions


Location: 3884553..3895373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG483_RS20465 (CG483_020415) - 3884553..3884798 (-) 246 WP_012096138.1 glutaredoxin family protein -
  CG483_RS20470 (CG483_020420) rpoN 3884808..3886115 (-) 1308 WP_087095556.1 RNA polymerase factor sigma-54 -
  CG483_RS23875 (CG483_020425) - 3886630..3886731 (-) 102 Protein_3923 GntR family transcriptional regulator -
  CG483_RS20480 (CG483_020430) - 3886830..3887774 (-) 945 Protein_3924 T7SS effector LXG polymorphic toxin -
  CG483_RS20485 (CG483_020435) - 3887986..3889020 (+) 1035 WP_239430992.1 tetratricopeptide repeat protein -
  CG483_RS20490 (CG483_020440) - 3889020..3889208 (+) 189 WP_087095557.1 Phr family secreted Rap phosphatase inhibitor -
  CG483_RS23880 - 3889367..3889726 (-) 360 WP_239430993.1 tyrosine-type recombinase/integrase -
  CG483_RS23885 - 3889799..3890095 (-) 297 WP_239430994.1 phage integrase N-terminal SAM-like domain-containing protein -
  CG483_RS20505 (CG483_020455) - 3890781..3890987 (+) 207 WP_012096140.1 DUF1657 domain-containing protein -
  CG483_RS20510 (CG483_020460) - 3891078..3891566 (+) 489 WP_012096141.1 YhcN/YlaJ family sporulation lipoprotein -
  CG483_RS20515 (CG483_020465) spoVAC 3891601..3892077 (+) 477 WP_012096142.1 stage V sporulation protein AC -
  CG483_RS20520 (CG483_020470) spoVAD 3892078..3893094 (+) 1017 WP_012096143.1 stage V sporulation protein AD -
  CG483_RS20525 (CG483_020475) spoVAE 3893091..3893441 (+) 351 WP_012096144.1 stage V sporulation protein AE -
  CG483_RS20530 (CG483_020480) - 3893453..3893659 (+) 207 WP_012096145.1 DUF1657 domain-containing protein -
  CG483_RS20535 (CG483_020485) - 3893680..3894549 (+) 870 WP_087095558.1 DUF421 domain-containing protein -
  CG483_RS20540 (CG483_020490) clpP 3894792..3895373 (+) 582 WP_012096148.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21418.68 Da        Isoelectric Point: 5.0645

>NTDB_id=251889 CG483_RS20540 WP_012096148.1 3894792..3895373(+) (clpP) [Bacillus cytotoxicus strain CH_38]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHLYINSPGGSITAGMAIYDT
MQFIKPNVSTICIGMAASMGAFLLAAGEKGKRFALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLRDKLNKILAERTGQ
PLEVIERDTDRDNFMTAEKALEYGLIDRIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=251889 CG483_RS20540 WP_012096148.1 3894792..3895373(+) (clpP) [Bacillus cytotoxicus strain CH_38]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGCGCAATTGATGACAATGTAGCAAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCATTTATACATTAACAGCCCTGGTGGTTCTATTACAGCAGGTATGGCCATCTATGACACA
ATGCAGTTCATTAAGCCAAACGTATCAACTATTTGTATCGGTATGGCAGCATCTATGGGTGCATTCCTACTTGCAGCTGG
TGAAAAAGGAAAACGCTTCGCACTTCCAAACAGTGAAGTTATGATCCACCAACCACTTGGTGGTGCACAAGGACAAGCAA
CTGAAATTGAAATCGCTGCAAAACGCATCCTATTCCTACGCGATAAATTAAACAAAATCCTTGCAGAACGCACAGGCCAA
CCACTAGAAGTCATCGAACGCGACACAGACCGTGACAACTTCATGACAGCCGAAAAAGCACTAGAATACGGCCTAATCGA
TAGAATCTTTACAAACCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7GUT3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

92.188

99.482

0.917
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.085

97.409

0.663
  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601
  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601
  clpP Streptococcus pneumoniae TIGR4

59.375

99.482

0.591
  clpP Streptococcus pneumoniae D39

59.375

99.482

0.591
  clpP Lactococcus lactis subsp. cremoris KW2

59.375

99.482

0.591
  clpP Streptococcus pneumoniae Rx1

59.375

99.482

0.591
  clpP Streptococcus pneumoniae R6

59.375

99.482

0.591
  clpP Streptococcus pyogenes JRS4

57.812

99.482

0.575
  clpP Streptococcus pyogenes MGAS315

57.812

99.482

0.575
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

57.292

99.482

0.57
  clpP Streptococcus mutans UA159

56.995

100

0.57

Multiple sequence alignment