Detailed information NTG0249113

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: CP942_RS14200
• Genome accession: NZ_CP023666
• Coordinates: 2889034..2889606 (+)
• Length: 190 a.a.
• NCBI ID: WP_025810658.1
• Uniprot ID: A0A6I7TPT5
• Organism: Bacillus paralicheniformis strain Bac48
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2884034..2894606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CP942_RS14175	cls	2884523..2885971 (-)	1449	WP_025810656.1	cardiolipin synthase	-
CP942_RS14180	-	2886219..2886662 (+)	444	WP_025810657.1	YwnF family protein	-
CP942_RS14185	-	2886713..2887210 (-)	498	WP_020453226.1	GNAT family N-acetyltransferase	-
CP942_RS14190	-	2887404..2888279 (+)	876	WP_023857113.1	M23 family metallopeptidase	-
CP942_RS14195	-	2888415..2889020 (+)	606	WP_020453224.1	RNA polymerase sigma factor	-
CP942_RS14200	clpP	2889034..2889606 (+)	573	WP_025810658.1	ATP-dependent Clp protease proteolytic subunit	Regulator
CP942_RS14205	-	2889654..2890004 (-)	351	WP_003185936.1	P-II family nitrogen regulator	-
CP942_RS14210	-	2890023..2891234 (-)	1212	WP_023857117.1	ammonium transporter	-
CP942_RS14215	-	2891383..2892681 (-)	1299	WP_023857118.1	hemolysin family protein	-
CP942_RS14220	-	2892842..2893798 (+)	957	WP_105979570.1	magnesium transporter CorA family protein	-
CP942_RS14225	-	2893859..2894266 (+)	408	WP_023857120.1	CBS domain-containing protein	-

Sequence

Protein

• Length: 190 a.a.
• Molecular weight: 21088.23 Da
• Isoelectric Point: 5.3555

>NTDB_id=249113 CP942_RS14200 WP_025810658.1 2889034..2889606(+) (clpP) [Bacillus paralicheniformis strain Bac48]
MNTIPYVIEKTAAGERSYDIFSRLLKDRIIMIGSEFNDDLANRVTAQLLFLSAEDNEKDISIYINSPGGSTSAGYAILDT
MDYVKPDVRTICVGMAASMGAILLAGGTKGKRYALKNSEIMIHQPLGGVKGQATDMEISAKRIIKLREKIEHFFHERTGQ
PIERLKADMERDYFMDADEAKAYGVIDAVL

Nucleotide

• Length: 573 bp

>NTDB_id=249113 CP942_RS14200 WP_025810658.1 2889034..2889606(+) (clpP) [Bacillus paralicheniformis strain Bac48]
ATGAACACCATACCTTACGTCATTGAGAAAACGGCTGCCGGTGAAAGATCGTACGATATTTTTTCCAGACTTTTAAAAGA
CCGGATCATTATGATCGGCTCTGAATTCAACGATGACCTCGCCAATCGGGTCACCGCCCAGTTGCTGTTTTTGTCAGCCG
AAGACAATGAAAAAGACATTTCGATCTATATCAACAGCCCGGGCGGATCAACTTCCGCGGGATATGCGATTTTGGATACG
ATGGACTATGTGAAGCCGGATGTCCGCACGATCTGCGTCGGAATGGCAGCTTCCATGGGAGCGATTCTCCTCGCCGGCGG
AACAAAAGGCAAACGGTATGCGCTCAAAAACAGCGAAATCATGATCCATCAGCCGCTCGGCGGCGTCAAAGGACAGGCGA
CAGACATGGAGATTTCAGCGAAGCGGATCATCAAACTGAGGGAAAAAATCGAGCACTTTTTTCACGAACGAACGGGCCAG
CCCATTGAAAGACTAAAAGCCGACATGGAACGTGATTATTTTATGGATGCGGACGAAGCGAAGGCATACGGTGTGATTGA
CGCCGTTTTATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (14-190)

3D structure

• AlphaFold DB: A0A6I7TPT5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	65.263	100	0.653
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	61.497	98.421	0.605
clpP	Streptococcus thermophilus LMG 18311	55.556	99.474	0.553
clpP	Streptococcus thermophilus LMD-9	55.556	99.474	0.553
clpP	Streptococcus pyogenes MGAS315	55.026	99.474	0.547
clpP	Streptococcus pyogenes JRS4	55.026	99.474	0.547
clpP	Streptococcus pneumoniae D39	54.497	99.474	0.542
clpP	Streptococcus mutans UA159	54.497	99.474	0.542
clpP	Streptococcus pneumoniae Rx1	54.497	99.474	0.542
clpP	Streptococcus pneumoniae R6	54.497	99.474	0.542
clpP	Streptococcus pneumoniae TIGR4	54.497	99.474	0.542
clpP	Lactococcus lactis subsp. cremoris KW2	52.91	99.474	0.526
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	51.852	99.474	0.516