Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   CO687_RS03325 Genome accession   NZ_CP023511
Coordinates   673697..675850 (+) Length   717 a.a.
NCBI ID   WP_096754925.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_371     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 668697..680850
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO687_RS03300 (CO687_03300) - 669636..669926 (+) 291 WP_045504760.1 thiamine-binding protein -
  CO687_RS03305 (CO687_03305) - 669889..670641 (+) 753 WP_096754923.1 ABC transporter permease -
  CO687_RS03310 (CO687_03310) - 670682..671683 (+) 1002 WP_096754924.1 ABC transporter substrate-binding protein -
  CO687_RS03315 (CO687_03315) - 671683..672405 (+) 723 WP_061596031.1 ABC transporter ATP-binding protein -
  CO687_RS03320 (CO687_03320) rpsD 672674..673285 (+) 612 WP_008810013.1 30S ribosomal protein S4 -
  CO687_RS03325 (CO687_03325) comA 673697..675850 (+) 2154 WP_096754925.1 peptide cleavage/export ABC transporter ComA Regulator
  CO687_RS03330 (CO687_03330) comB 675860..677218 (+) 1359 WP_096754926.1 competence pheromone export protein ComB Regulator
  CO687_RS03335 (CO687_03335) lytF 677337..678986 (-) 1650 WP_096754927.1 GBS Bsp-like repeat-containing protein Regulator
  CO687_RS03340 (CO687_03340) purD 679231..680490 (+) 1260 WP_096754928.1 phosphoribosylamine--glycine ligase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80676.73 Da        Isoelectric Point: 7.2116

>NTDB_id=247946 CO687_RS03325 WP_096754925.1 673697..675850(+) (comA) [Streptococcus gordonii strain FDAARGOS_371]
MKFRKRHYRAQVDTRDCGVAALAMVFGYYGSYFSLATLREKAKTTNDGTTALGLVKVAEGLNFETRAFKADMGIFDLEDV
SYPFIVHVLKEGKLLHYYVVTGQDKHTIHIADPDPQVKMTKISRERFEQEWTGITIFLAPSPAYKPSQEKKNGLLDFIPL
LIKQKGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDHMKTTLGMISIGLIIVYILQQFLSYAQEYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEIVSRFTDANRIIDALASTILSIFLDVSIVSIIAIVLFSQNSSLFFLTLLGIPVYAL
IIFLFMKPFEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVTYLKKSFAYGRSESLQKVLKAAARL
ILNVLILWLGATLVMDQKISLGQLITYNTLLVYFTNPLENIINLQTKLQSARVANERLNEVYLVQSEFNEEKLIKDLSHF
PADIDFRGVSYKYGYGANVLSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYGPNQGDICLGGVNLNQLDKQALRQYI
NYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIRSDIERMPLNYQTELSADGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIIDNLMALDKTIIFIAHRLTIAERSEQVVVLDQGRIVESGRHKELIEKEGFYHHLINS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=247946 CO687_RS03325 WP_096754925.1 673697..675850(+) (comA) [Streptococcus gordonii strain FDAARGOS_371]
ATGAAATTTAGGAAACGGCATTACAGAGCACAAGTTGATACTAGGGATTGCGGAGTGGCAGCTCTGGCTATGGTTTTTGG
TTATTATGGATCGTATTTTTCCTTGGCTACACTGCGAGAAAAGGCAAAAACGACTAATGATGGCACAACAGCTTTGGGTT
TGGTAAAAGTTGCTGAGGGCTTAAATTTTGAGACAAGGGCTTTTAAAGCTGATATGGGAATCTTTGATCTGGAAGATGTA
TCTTATCCTTTCATCGTTCATGTACTTAAGGAAGGGAAGCTCCTGCATTATTATGTTGTGACGGGCCAAGATAAACACAC
GATTCATATTGCAGACCCAGATCCTCAAGTTAAGATGACAAAGATTTCGCGAGAGCGTTTCGAACAGGAGTGGACAGGGA
TTACCATTTTCCTAGCTCCTAGTCCAGCCTATAAACCTAGTCAGGAAAAGAAAAATGGACTTTTAGACTTCATTCCCTTA
TTGATTAAGCAGAAGGGATTGATTGCTAATATTGTACTTGCAACTTTGCTGGTAACGTTGATCAATATTGTTGGATCCTA
CTACCTTCAATCGATTATTGATACTTATGTGCCTGATCATATGAAAACGACGCTGGGTATGATTTCTATCGGCTTGATTA
TTGTCTACATTTTGCAGCAATTCTTGTCTTATGCCCAAGAATATTTACTCTTGGTTTTGGGGCAACGTCTATCAATTGAT
GTGATCTTATCCTATATCAAGCACGTTTTTCAGCTACCTATGTCATTTTTCGCGACAAGGCGGACAGGGGAAATTGTTTC
TCGTTTTACGGATGCCAATCGGATTATTGATGCCTTGGCCAGTACAATCTTGTCTATTTTCTTGGATGTGTCGATTGTAT
CGATCATTGCGATTGTTCTTTTTTCACAAAATAGCAGTCTTTTCTTTTTGACCTTGCTAGGAATCCCAGTTTACGCGCTC
ATTATTTTTCTTTTTATGAAGCCTTTTGAAAAGATGAATCATGAGACGATGGAAGCAAATAGTCTGTTGTCGTCTTCCAT
TATTGAAGATATCAATGGGATTGAAACGATCAAGTCTTTGACCAGCGAAAAACAACGTTATCAGAAGATTGACAAGGAAT
TTGTGACTTATCTGAAAAAGTCTTTTGCATATGGACGTTCTGAGAGTTTACAAAAAGTCTTGAAAGCAGCAGCTCGTTTG
ATTTTAAACGTCTTGATTTTATGGCTAGGAGCCACACTTGTCATGGATCAAAAAATCAGTCTTGGTCAGCTCATCACTTA
TAATACACTTCTAGTCTACTTTACTAATCCTTTAGAAAATATTATCAATTTGCAAACGAAATTACAGTCTGCTCGTGTAG
CCAACGAGCGTCTCAATGAGGTCTATTTAGTCCAGTCTGAGTTTAATGAAGAGAAGCTTATTAAAGACTTGAGCCACTTT
CCGGCTGACATCGATTTTCGTGGAGTCAGTTATAAGTATGGCTATGGGGCCAATGTATTATCAGAAATTGACTTGCATAT
TCCTGCTGGAAGTAAGACCAGCTTTGTTGGTGTATCAGGATCAGGAAAAACAACCTTGGCCAAGATGATGGTGCATTTTT
ACGGTCCGAATCAAGGGGATATTTGTCTGGGAGGTGTCAATCTCAATCAGCTGGATAAGCAGGCACTGCGCCAATATATC
AACTATCTTCCCCAGCAACCTTATGTTTTTAATGGAACTATTTTGGAAAATTTACTCTTAGGTGCGCGTGAAGGCACGAC
TCAAGAAGATATTCTGCGGGCGGTAGAATTGGCAGAAATTAGGTCGGATATTGAGCGGATGCCTCTCAATTATCAGACAG
AGCTATCAGCAGATGGAGCAGGGATTTCAGGTGGTCAACGCCAGCGTATTGCTCTAGCGAGGGCTCTCTTGACAGATGCG
CCAGTGCTTATCTTAGATGAAGCAACGAGTAGTCTGGATATTCTAACAGAGAAGCGGATCATTGATAATCTGATGGCGCT
TGATAAGACGATTATTTTCATCGCGCATCGTTTGACTATTGCGGAACGTTCGGAGCAGGTGGTCGTTTTGGATCAAGGTA
GGATTGTTGAGAGTGGAAGACATAAGGAGCTGATCGAAAAAGAAGGTTTTTACCACCATTTGATCAATAGTTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

97.49

100

0.975
  comA Streptococcus mitis NCTC 12261

81.032

100

0.81
  comA Streptococcus pneumoniae D39

80.893

100

0.809
  comA Streptococcus pneumoniae R6

80.893

100

0.809
  comA Streptococcus pneumoniae Rx1

80.893

100

0.809
  comA Streptococcus mitis SK321

80.614

100

0.806
  comA Streptococcus pneumoniae TIGR4

80.474

100

0.805
  comA/nlmT Streptococcus mutans UA159

64.854

100

0.649

Multiple sequence alignment