Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   CO686_RS06340 Genome accession   NZ_CP023507
Coordinates   1267050..1267640 (-) Length   196 a.a.
NCBI ID   WP_000613468.1    Uniprot ID   A0AAW7W8Y7
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1258124..1269005 1267050..1267640 within 0


Gene organization within MGE regions


Location: 1258124..1269005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS06285 (CO686_06285) ftsX 1258124..1259050 (-) 927 WP_000625556.1 permease-like cell division protein FtsX -
  CO686_RS06290 (CO686_06290) ftsE 1259043..1259735 (-) 693 WP_000022275.1 cell division ATP-binding protein FtsE -
  CO686_RS06305 (CO686_06305) - 1260959..1261615 (-) 657 WP_000268643.1 CBS domain-containing protein -
  CO686_RS06310 (CO686_06310) - 1262030..1262740 (-) 711 WP_000062204.1 ABC transporter ATP-binding protein -
  CO686_RS06315 (CO686_06315) - 1262740..1263504 (-) 765 WP_001186014.1 ABC transporter ATP-binding protein -
  CO686_RS06320 (CO686_06320) - 1263504..1264460 (-) 957 WP_000856263.1 branched-chain amino acid ABC transporter permease -
  CO686_RS06325 (CO686_06325) - 1264464..1265333 (-) 870 WP_000941413.1 branched-chain amino acid ABC transporter permease -
  CO686_RS06330 (CO686_06330) - 1265453..1266613 (-) 1161 WP_000726124.1 ABC transporter substrate-binding protein -
  CO686_RS06335 (CO686_06335) - 1266702..1266971 (-) 270 WP_000462109.1 YlbG family protein -
  CO686_RS06340 (CO686_06340) clpP 1267050..1267640 (-) 591 WP_000613468.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  CO686_RS06345 (CO686_06345) upp 1267820..1268449 (-) 630 WP_000515974.1 uracil phosphoribosyltransferase -
  CO686_RS06350 (CO686_06350) - 1268538..1269005 (-) 468 WP_071851366.1 cytidine/deoxycytidylate deaminase family protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21348.34 Da        Isoelectric Point: 4.4829

>NTDB_id=247865 CO686_RS06340 WP_000613468.1 1267050..1267640(-) (clpP) [Streptococcus oralis strain FDAARGOS_367]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGK
SVEQVHADAERDYWMSAQETLEYGFIDEIMANNSLS

Nucleotide


Download         Length: 591 bp        

>NTDB_id=247865 CO686_RS06340 WP_000613468.1 1267050..1267640(-) (clpP) [Streptococcus oralis strain FDAARGOS_367]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGATATTTACTCTCGTCTTCTGAAAGACCGCAT
CATCATGCTAACAGGTCCAGTTGAAGACAACATGGCCAACTCCGTTATCGCCCAATTACTTTTCTTGGATGCCCAAGACA
GCACAAAAGATATTTACCTTTATGTCAATACACCTGGGGGCTCTGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACAATCGTTATGGGGATGGCTGCATCCATGGGGACTGTTATTGCATCAAGTGGCGCCAA
AGGCAAACGTTTCATGCTTCCAAATGCGGAGTACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAAA
CCGATATGGCAATCGCTGCAGAGCACTTGCTCAAAACTCGTAAGACTTTGGAGCAAATCCTTGCAGATAACTCTGGTAAA
TCAGTCGAGCAAGTTCATGCAGATGCGGAACGTGATTACTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCTTTAAGCTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

95.918

100

0.959
  clpP Streptococcus pneumoniae D39

95.918

100

0.959
  clpP Streptococcus pneumoniae R6

95.918

100

0.959
  clpP Streptococcus pneumoniae TIGR4

95.918

100

0.959
  clpP Streptococcus thermophilus LMD-9

91.795

99.49

0.913
  clpP Streptococcus thermophilus LMG 18311

91.795

99.49

0.913
  clpP Streptococcus pyogenes JRS4

91.795

99.49

0.913
  clpP Streptococcus pyogenes MGAS315

91.795

99.49

0.913
  clpP Streptococcus mutans UA159

88.205

99.49

0.878
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.179

99.49

0.867
  clpP Lactococcus lactis subsp. cremoris KW2

86.667

99.49

0.862
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.513

98.469

0.566
  clpP Bacillus subtilis subsp. subtilis str. 168

56.771

97.959

0.556

Multiple sequence alignment