Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   CO686_RS04255 Genome accession   NZ_CP023507
Coordinates   848225..848932 (+) Length   235 a.a.
NCBI ID   WP_000722058.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 843225..853932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS04230 (CO686_04230) - 843522..844193 (+) 672 WP_070535354.1 GTP pyrophosphokinase family protein -
  CO686_RS04235 (CO686_04235) - 844177..844995 (+) 819 WP_070535352.1 NAD kinase -
  CO686_RS04240 (CO686_04240) - 844992..845888 (+) 897 WP_096753550.1 RluA family pseudouridine synthase -
  CO686_RS04245 (CO686_04245) pta 845932..846906 (+) 975 WP_049549926.1 phosphate acetyltransferase -
  CO686_RS04250 (CO686_04250) mutY 846989..848167 (+) 1179 WP_096753551.1 A/G-specific adenine glycosylase -
  CO686_RS04255 (CO686_04255) micA 848225..848932 (+) 708 WP_000722058.1 response regulator YycF Regulator
  CO686_RS04260 (CO686_04260) micB 848925..850274 (+) 1350 WP_096753552.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CO686_RS04265 (CO686_04265) vicX 850276..851085 (+) 810 WP_049518757.1 MBL fold metallo-hydrolase Regulator
  CO686_RS04270 (CO686_04270) - 851120..851467 (-) 348 WP_049518755.1 thiol reductase thioredoxin -
  CO686_RS04275 (CO686_04275) - 851579..853297 (-) 1719 WP_000222125.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27005.85 Da        Isoelectric Point: 4.6177

>NTDB_id=247854 CO686_RS04255 WP_000722058.1 848225..848932(+) (micA) [Streptococcus oralis strain FDAARGOS_367]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=247854 CO686_RS04255 WP_000722058.1 848225..848932(+) (micA) [Streptococcus oralis strain FDAARGOS_367]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGTTATGA
AGTTGTAACAGCCTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCTGAGCAACCAGATATTATTATCCTCGACTTAA
TGCTACCTGAAATTGATGGTTTAGAAGTTGCTAAAGCTATTCGTAAGACTAGTAGCGTGCCGATTATCATGCTATCAGCT
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGACGATTATGTTACAAAACCTTTCTCAAACCGTGA
ATTGCAGGCTCGTGTCAAGGCCCTGCTTCGTCGTACAGACCTAGTTTCTGTGGATAGCCAAGAGTCTGATGAGAAGAAGA
CGCAACCTTTACAAATTGGTGATTTGGAAATCGTTCCAGATGCTTACGTGGCGAAGAAATATGGTGAGGAATTAGATTTG
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCGTCTCATATTGGTCAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTATGGGGTTATGACTATTTTGGTGATGTTCGTACAGTGGACGTGACCATTAGACGCTTACGTGAGAAAATCGAAGATA
CTCCAAGTCGTCCAGAGTACATTCTCACACGTCGTGGTGTTGGATACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

43.723

98.298

0.43
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

37.179

99.574

0.37

Multiple sequence alignment