Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   CO686_RS04260 Genome accession   NZ_CP023507
Coordinates   848925..850274 (+) Length   449 a.a.
NCBI ID   WP_096753552.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 843925..855274
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS04235 (CO686_04235) - 844177..844995 (+) 819 WP_070535352.1 NAD kinase -
  CO686_RS04240 (CO686_04240) - 844992..845888 (+) 897 WP_096753550.1 RluA family pseudouridine synthase -
  CO686_RS04245 (CO686_04245) pta 845932..846906 (+) 975 WP_049549926.1 phosphate acetyltransferase -
  CO686_RS04250 (CO686_04250) mutY 846989..848167 (+) 1179 WP_096753551.1 A/G-specific adenine glycosylase -
  CO686_RS04255 (CO686_04255) micA 848225..848932 (+) 708 WP_000722058.1 response regulator YycF Regulator
  CO686_RS04260 (CO686_04260) micB 848925..850274 (+) 1350 WP_096753552.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CO686_RS04265 (CO686_04265) vicX 850276..851085 (+) 810 WP_049518757.1 MBL fold metallo-hydrolase Regulator
  CO686_RS04270 (CO686_04270) - 851120..851467 (-) 348 WP_049518755.1 thiol reductase thioredoxin -
  CO686_RS04275 (CO686_04275) - 851579..853297 (-) 1719 WP_000222125.1 phospho-sugar mutase -
  CO686_RS04280 (CO686_04280) - 853708..854862 (+) 1155 WP_000722099.1 DUF4352 domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51636.01 Da        Isoelectric Point: 4.6122

>NTDB_id=247855 CO686_RS04260 WP_096753552.1 848925..850274(+) (micB) [Streptococcus oralis strain FDAARGOS_367]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LTIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVSPDFIKVSLDETNRMMRMVTDLLHLSRIDNATTRLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=247855 CO686_RS04260 WP_096753552.1 848925..850274(+) (micB) [Streptococcus oralis strain FDAARGOS_367]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGTGATTTTATCTTTATCCTGATTTTACTTGGCTTTATCCTGGTGGT
GACCTTGCTGTTACTGGAAAATCGTCGGGATAATATCCGTCTGAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTGCAAGGAAGTACAGAAATCACCAATATCACCAATAATCTGAACGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAACAGTATTCTTTCTTACATGACAGATGGCGT
TCTTGCGACCAATCGTCGTGGCCAGATTACCATGATTAATGACATGGCCAAGAAACAGCTCGGTGTGCAGAAAGAAGATG
TTCTGAATAAAAGCATCCTCGAATTGCTTAAGATAGAAGATGAGTATGAGCTGCGTGACCTGATTACACAGATTCCTGAG
TTGACGATTGACTCCCAGGATGTGAATGGTGAATATCTAAGCCTTCGTGTACGTTTTGCTCTGGTTCGCCGTGAGTCAGG
TTTCATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAACAGGAGAAGGAAGAGCGTGAGCGAAGACTCTTTGTTT
CGAACGTGAGTCACGAGTTGCGAACTCCTTTGACCAGTGTTAAATCTTATCTTGAAGCCTTGGACGAGGGGGCCCTATAT
GATCCTGTTTCCCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTTTTGCA
TCTCTCTCGTATTGATAATGCGACCACTCGGTTGGATGTGGAATTGATTAATTTTACTGCATTCATCACTTTTATTCTCA
ACCGCTTTGATAAGATGAGAAGTCAGGATGACGAGAAAAAATATGAGCTTGTCAGAGATTACCCTATTAATTCAGTTTGG
ATCGAGATTGATACCGATAAGATGACTCAGGTGATTGATAATATTCTTAACAATGCCATCAAGTACTCACCAGATGGTGG
CAAAATCACTGTCAGCATGAAAACTACTGATGACCAGATGATTTTATCTATTAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCAAAGATTTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGAGCTCAAGGTGGAACTGGTCTAGGT
CTGGCTATAGCAAAAGAAATCATCAAACAACACAATGGCTTTATTTGGGCCAAAAGTGAATACGGTAAGGGATCAACCTT
TACCATCGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGATTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.066

97.773

0.871
  vicK Streptococcus mutans UA159

70.398

89.532

0.63

Multiple sequence alignment