Detailed information NTG0247424

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: CO204_RS05575
• Genome accession: NZ_CP023477
• Coordinates: 1074471..1075313 (-)
• Length: 280 a.a.
• NCBI ID: WP_002262865.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain LAR01
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1069471..1080313

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO204_RS05565 (CO204_05550)	trmFO	1070552..1071886 (-)	1335	WP_002265838.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
CO204_RS05570 (CO204_05555)	topA	1072259..1074376 (-)	2118	WP_106006746.1	type I DNA topoisomerase	-
CO204_RS05575 (CO204_05560)	dprA	1074471..1075313 (-)	843	WP_002262865.1	DNA-processing protein DprA	Machinery gene
CO204_RS05585 (CO204_05570)	-	1075480..1075761 (-)	282	WP_106006747.1	hypothetical protein	-
CO204_RS05590 (CO204_05575)	-	1075833..1076849 (-)	1017	WP_002265840.1	siderophore ABC transporter substrate-binding protein	-
CO204_RS05595 (CO204_05580)	-	1076897..1077703 (-)	807	WP_019313220.1	ABC transporter ATP-binding protein	-
CO204_RS05600 (CO204_05585)	-	1077700..1078671 (-)	972	WP_002278555.1	iron chelate uptake ABC transporter family permease subunit	-
CO204_RS05605 (CO204_05590)	-	1078668..1079630 (-)	963	WP_019313219.1	iron chelate uptake ABC transporter family permease subunit	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31332.27 Da
• Isoelectric Point: 9.1954

>NTDB_id=247424 CO204_RS05575 WP_002262865.1 1074471..1075313(-) (dprA) [Streptococcus mutans strain LAR01]
MDNFQLFKLKKAGLTNLNILNIIDYEERTQKSLSLRDMAVVSKNKKPLIFMEHYKNLDSKALRKEFNRFPSLSILDKEYP
LELKNIYNPPVLLFYQGDLDLLARPKLAVVGSRNASQMGVAAVKKIIQDLSKQFVIISGLARGIDTAAHLASLKSGGATI
AVIGTGLDVHYPKENRRLQDYIAKNHLLLSEYEAQSQPLKYHFPERNRIIAGLSQGVMVAEAKIRSGSLITCERAMEEGR
DVFVVPGNILDGQSEGCHHLIQEGAKCITSGFDILNEFNF

Nucleotide

• Length: 843 bp

>NTDB_id=247424 CO204_RS05575 WP_002262865.1 1074471..1075313(-) (dprA) [Streptococcus mutans strain LAR01]
ATGGATAATTTTCAACTATTTAAACTTAAAAAAGCTGGTCTAACAAATCTGAATATCTTAAATATTATTGATTATGAAGA
GAGGACACAAAAATCCTTGTCTCTTCGTGATATGGCTGTTGTTTCCAAAAATAAAAAGCCTTTAATTTTTATGGAACATT
ACAAGAATCTTGATAGCAAAGCATTACGCAAAGAATTTAATCGTTTTCCTTCTTTATCCATTTTGGACAAAGAATATCCC
TTAGAACTTAAAAATATTTATAATCCGCCTGTTCTTCTATTTTATCAGGGAGACTTAGACTTGCTAGCTCGGCCTAAATT
AGCAGTAGTTGGTTCTCGCAACGCCAGTCAAATGGGAGTAGCTGCTGTTAAAAAGATCATACAAGACTTAAGTAAGCAAT
TTGTTATTATTAGCGGTTTAGCGCGTGGTATTGATACTGCAGCACATTTAGCAAGTCTTAAAAGTGGTGGAGCAACAATT
GCGGTCATCGGTACTGGACTAGATGTTCATTATCCTAAAGAAAATCGAAGACTGCAGGATTATATTGCAAAGAATCATTT
GCTCTTATCAGAATATGAAGCACAGAGTCAACCTCTTAAGTATCATTTTCCTGAGCGGAACCGCATTATTGCTGGGTTAT
CTCAAGGTGTTATGGTAGCAGAAGCAAAAATTCGTTCGGGTAGTCTGATTACTTGTGAACGTGCTATGGAAGAAGGACGC
GATGTTTTTGTTGTACCAGGAAATATTTTAGACGGCCAGTCAGAAGGATGCCATCACCTGATTCAAGAAGGAGCAAAATG
CATTACATCAGGCTTTGATATTTTAAATGAGTTTAACTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	100	100	1
dprA/cilB/dalA	Streptococcus mitis SK321	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.857	100	0.629
dprA	Lactococcus lactis subsp. cremoris KW2	58.273	99.286	0.579
dprA	Legionella pneumophila strain ERS1305867	44.77	85.357	0.382
dprA	Staphylococcus aureus N315	38.258	94.286	0.361