Detailed information NTG0247411

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: CO204_RS02575
• Genome accession: NZ_CP023477
• Coordinates: 476060..476674 (+)
• Length: 204 a.a.
• NCBI ID: WP_255262720.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain LAR01
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 471060..481674

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO204_RS02560 (CO204_02560)	-	472586..473680 (+)	1095	WP_019313372.1	cystathionine gamma-synthase	-
CO204_RS02565 (CO204_02565)	-	473695..474858 (+)	1164	WP_019313371.1	MalY/PatB family protein	-
CO204_RS02570 (CO204_02570)	upp	475171..475800 (+)	630	WP_002275750.1	uracil phosphoribosyltransferase	-
CO204_RS02575 (CO204_02575)	clpP	476060..476674 (+)	615	WP_255262720.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
CO204_RS02580 (CO204_02580)	-	476790..477230 (+)	441	WP_019313370.1	YlbF family regulator	-
CO204_RS02585 (CO204_02585)	-	477237..477485 (+)	249	WP_002262674.1	YlbG family protein	-
CO204_RS02590 (CO204_02590)	-	477588..478760 (+)	1173	WP_019313369.1	ABC transporter substrate-binding protein	-
CO204_RS02595 (CO204_02595)	-	478844..479713 (+)	870	WP_002262676.1	branched-chain amino acid ABC transporter permease	-
CO204_RS02600 (CO204_02600)	-	479717..480673 (+)	957	WP_002266832.1	branched-chain amino acid ABC transporter permease	-
CO204_RS02605 (CO204_02605)	-	480673..481437 (+)	765	WP_002262678.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 204 a.a.
• Molecular weight: 22679.13 Da
• Isoelectric Point: 5.3673

>NTDB_id=247411 CO204_RS02575 WP_255262720.1 476060..476674(+) (clpP) [Streptococcus mutans strain LAR01]
MELKEKYSMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINSPGGSVSAG
LAIVDTMNFIKSDVQTIVMGIAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGGGTQQSDMAIAAEQLLKTRKKLEK
ILSDNSGKTIKQIHKDAERDYWMDAKETLKYGFIDEIMENNELK

Nucleotide

• Length: 615 bp

>NTDB_id=247411 CO204_RS02575 WP_255262720.1 476060..476674(+) (clpP) [Streptococcus mutans strain LAR01]
ATTGAATTAAAGGAGAAATACAGTATGATTCCTGTAGTTATTGAACAAACGAGCCGTGGTGAACGCTCTTATGATATTTA
TTCACGTCTATTAAAAGATCGTATTATTATGTTGACTGGTCCTGTTGAAGACAATATGGCAAATTCCATTATTGCTCAGT
TACTGTTTCTTGATGCACAAGATAATACCAAAGACATTTATCTTTATATTAATTCACCGGGTGGTTCTGTTTCAGCTGGT
CTTGCTATTGTTGATACGATGAACTTTATTAAGTCTGATGTTCAAACGATTGTTATGGGTATTGCTGCTTCCATGGGAAC
AATCATCGCTTCTAGCGGTGCCAAAGGAAAACGTTTTATGTTACCAAATGCAGAATATCTTATCCATCAGCCAATGGGCG
GTACAGGCGGTGGCACACAGCAGTCTGATATGGCTATTGCTGCCGAACAATTGCTTAAAACACGCAAAAAGTTAGAAAAG
ATTCTATCGGATAATTCTGGAAAAACAATAAAACAAATTCATAAGGATGCTGAACGTGATTATTGGATGGATGCTAAGGA
AACATTAAAGTATGGCTTCATCGATGAAATCATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (19-200)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	100	100	1
clpP	Streptococcus pyogenes MGAS315	90.816	96.078	0.873
clpP	Streptococcus pyogenes JRS4	90.816	96.078	0.873
clpP	Streptococcus thermophilus LMD-9	87.755	96.078	0.843
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.755	96.078	0.843
clpP	Streptococcus thermophilus LMG 18311	87.755	96.078	0.843
clpP	Lactococcus lactis subsp. cremoris KW2	87.245	96.078	0.838
clpP	Streptococcus pneumoniae Rx1	86.154	95.588	0.824
clpP	Streptococcus pneumoniae D39	86.154	95.588	0.824
clpP	Streptococcus pneumoniae TIGR4	86.154	95.588	0.824
clpP	Streptococcus pneumoniae R6	86.154	95.588	0.824
clpP	Bacillus subtilis subsp. subtilis str. 168	55.838	96.569	0.539
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	94.608	0.539