Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C7M30_RS07715 Genome accession   NZ_CP028218
Coordinates   1499685..1500326 (-) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain SRCM102756     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1494685..1505326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M30_RS07695 (C7M30_01541) mneP 1494744..1495637 (+) 894 WP_015252717.1 manganese transporter MneP -
  C7M30_RS07700 (C7M30_01542) ydfL 1495749..1496561 (+) 813 WP_064671994.1 MerR family transcriptional regulator -
  C7M30_RS07705 (C7M30_01543) ydfK 1496651..1497340 (+) 690 WP_064671993.1 DUF554 domain-containing protein -
  C7M30_RS07710 (C7M30_01544) pleJ 1497398..1499569 (-) 2172 WP_160244221.1 MMPL family transporter -
  C7M30_RS07715 (C7M30_01545) vraR 1499685..1500326 (-) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  C7M30_RS07720 (C7M30_01546) ydfH 1500319..1501542 (-) 1224 WP_160244222.1 two-component system sensor histidine kinase YdfH -
  C7M30_RS07725 - 1501810..1501953 (+) 144 WP_160244223.1 hypothetical protein -
  C7M30_RS07730 (C7M30_01547) - 1501950..1502129 (+) 180 WP_072175193.1 hypothetical protein -
  C7M30_RS07735 (C7M30_01548) ydfG 1502215..1502658 (+) 444 WP_014475936.1 carboxymuconolactone decarboxylase family protein -
  C7M30_RS07740 (C7M30_01549) ydfF 1502726..1503406 (-) 681 WP_014478969.1 winged helix-turn-helix domain-containing protein -
  C7M30_RS07745 (C7M30_01550) ydfE 1503496..1504119 (+) 624 WP_029725823.1 flavin reductase family protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=240496 C7M30_RS07715 WP_003244318.1 1499685..1500326(-) (vraR) [Bacillus subtilis strain SRCM102756]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=240496 C7M30_RS07715 WP_003244318.1 1499685..1500326(-) (vraR) [Bacillus subtilis strain SRCM102756]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCGATCAGAGGGAATGTGCTGTTGCAGCCTGATATCCTCAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362

Multiple sequence alignment