Detailed information NTG0239002

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: QMA0248_RS07155
• Genome accession: NZ_CP022392
• Coordinates: 1462391..1462993 (-)
• Length: 200 a.a.
• NCBI ID: WP_071794733.1
• Uniprot ID: A0A3L8GDT3
• Organism: Streptococcus iniae strain QMA0248
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1457391..1467993

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMA0248_RS07125 (QMA0248_1441)	-	1457974..1458927 (-)	954	WP_016356098.1	branched-chain amino acid ABC transporter permease	-
QMA0248_RS07130 (QMA0248_1442)	-	1458931..1459800 (-)	870	WP_016356099.1	branched-chain amino acid ABC transporter permease	-
QMA0248_RS07135 (QMA0248_1443)	-	1459860..1461032 (-)	1173	WP_003101539.1	ABC transporter substrate-binding protein	-
QMA0248_RS07140 (QMA0248_1444)	-	1461171..1461449 (-)	279	WP_003101541.1	YlbG family protein	-
QMA0248_RS07145 (QMA0248_1445)	-	1461425..1461895 (-)	471	WP_016356100.1	YlbF family regulator	-
QMA0248_RS07150 (QMA0248_1446)	-	1462024..1462269 (-)	246	WP_003101546.1	hypothetical protein	-
QMA0248_RS07155 (QMA0248_1447)	clpP	1462391..1462993 (-)	603	WP_071794733.1	ATP-dependent Clp protease proteolytic subunit	Regulator
QMA0248_RS07160 (QMA0248_1448)	upp	1463209..1463838 (-)	630	WP_003101549.1	uracil phosphoribosyltransferase	-
QMA0248_RS07165 (QMA0248_1449)	-	1463983..1465635 (-)	1653	WP_003101552.1	polysaccharide biosynthesis protein	-
QMA0248_RS07170 (QMA0248_1450)	-	1465723..1467168 (+)	1446	WP_003101555.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 200 a.a.
• Molecular weight: 22166.52 Da
• Isoelectric Point: 6.3409

>NTDB_id=239002 QMA0248_RS07155 WP_071794733.1 1462391..1462993(-) (clpP) [Streptococcus iniae strain QMA0248]
MENTMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDHTKDIYLYVNTPGGSVSAGLAIV
DTMNFIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQSDMAIAAEHLLKTRHTLEKILAK
NSGKTIKQVHKDAERDYWMSAEETLKYGFIDEIMENNKLK

Nucleotide

• Length: 603 bp

>NTDB_id=239002 QMA0248_RS07155 WP_071794733.1 1462391..1462993(-) (clpP) [Streptococcus iniae strain QMA0248]
ATGGAGAATACTATGATTCCTGTAGTTATTGAACAAACAAGTCGTGGGGAGCGTTCTTACGATATTTACTCTCGTTTACT
AAAAGATCGGATCATCATGTTAACTGGTCCGGTCGAAGACAATATGGCTAACTCTGTCATTGCACAGTTGCTTTTTTTGG
ATGCACAAGATCACACTAAAGATATTTATCTTTATGTTAATACCCCAGGTGGTTCCGTTTCTGCTGGTTTAGCCATTGTT
GATACAATGAACTTTATTAAATCTGATGTTCAAACAATTGTCATGGGAATGGCTGCTTCCATGGGAACAATCATTGCCTC
ATCAGGGACTAAAGGGAAACGGTTCATGTTGCCAAATGCTGAATACATGATTCACCAACCAATGGGTGGTACAGGTGGTG
GTACGCAGCAATCAGATATGGCAATTGCTGCTGAACATCTCTTAAAAACACGTCACACTCTTGAAAAAATATTGGCAAAA
AATAGTGGAAAAACCATTAAACAAGTTCATAAAGATGCAGAACGTGATTATTGGATGAGTGCAGAAGAAACACTAAAATA
TGGCTTCATTGATGAAATTATGGAAAATAACAAACTTAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (15-196)

3D structure

• AlphaFold DB: A0A3L8GDT3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes JRS4	94.898	98	0.93
clpP	Streptococcus pyogenes MGAS315	94.898	98	0.93
clpP	Streptococcus mutans UA159	91.371	98.5	0.9
clpP	Streptococcus thermophilus LMD-9	90.816	98	0.89
clpP	Streptococcus thermophilus LMG 18311	90.816	98	0.89
clpP	Streptococcus pneumoniae R6	90.769	97.5	0.885
clpP	Streptococcus pneumoniae Rx1	90.769	97.5	0.885
clpP	Streptococcus pneumoniae D39	90.769	97.5	0.885
clpP	Streptococcus pneumoniae TIGR4	90.769	97.5	0.885
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.714	98	0.84
clpP	Lactococcus lactis subsp. cremoris KW2	85.204	98	0.835
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.477	96.5	0.545
clpP	Bacillus subtilis subsp. subtilis str. 168	56.842	95	0.54