Detailed information NTG0237845

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: BG910_RS05215
• Genome accession: NZ_CP022278
• Coordinates: 1055853..1057019 (+)
• Length: 388 a.a.
• NCBI ID: WP_089037149.1
• Uniprot ID: A0A220S544
• Organism: Neisseria chenwenguii strain 10023
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1050853..1062019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BG910_RS05200 (BG910_05195)	-	1051378..1051971 (+)	594	WP_089035926.1	DUF4390 domain-containing protein	-
BG910_RS05205 (BG910_05200)	-	1051975..1054104 (+)	2130	WP_089035927.1	PAS domain-containing sensor histidine kinase	-
BG910_RS05210 (BG910_05205)	-	1054091..1055371 (+)	1281	WP_089035928.1	sigma-54 dependent transcriptional regulator	-
BG910_RS05215 (BG910_05210)	dprA	1055853..1057019 (+)	1167	WP_089037149.1	DNA-processing protein DprA	Machinery gene
BG910_RS05220 (BG910_05215)	-	1057063..1057518 (+)	456	WP_089035929.1	DUF494 family protein	-
BG910_RS05225 (BG910_05220)	topA	1057608..1059932 (+)	2325	WP_089035930.1	type I DNA topoisomerase	-
BG910_RS05230 (BG910_05225)	-	1059989..1061050 (-)	1062	WP_089035931.1	NAD(P)-dependent alcohol dehydrogenase	-
BG910_RS05235 (BG910_05230)	frr	1061362..1061919 (+)	558	WP_089035932.1	ribosome recycling factor	-

Sequence

Protein

• Length: 388 a.a.
• Molecular weight: 41472.52 Da
• Isoelectric Point: 6.0479

>NTDB_id=237845 BG910_RS05215 WP_089037149.1 1055853..1057019(+) (dprA) [Neisseria chenwenguii strain 10023]
MDTNERLAWLQLALTPYIGAERFLVLLKHFGSASAALNAPADTIAKLAAHNQAATAWRDGEKRALAQKAAEAALQWETQA
GCRLMLLDDDDFPTMLTEGITPPPLLFLRGDVALLHKPAVAIVGSRHATPQAMRIAKDFGKALSEKGIPVVSGMAAGIDT
AAHQGALQASGGTVTVWGTGIDRIYPPSNRQLAYEIAERGLIVSEFPLDTRPLAGNFPRRNRLIAALSCATLVVEAAVES
GSLITAKLAAEMGREVMAVPGSIDNPHSKGCHKLIKEGAKLTECLDDIVQECPQLLQNTANPSYSINKRREKVQNETPPR
PETPAPVAMPSENVAHPLLDAMGYDPVHPDTLAQQTGQPAADVYAVLMELELDGIVASLPGGRYQRIS

Nucleotide

• Length: 1167 bp

>NTDB_id=237845 BG910_RS05215 WP_089037149.1 1055853..1057019(+) (dprA) [Neisseria chenwenguii strain 10023]
ATGGATACCAACGAACGTCTTGCGTGGCTGCAACTCGCGCTCACGCCCTATATCGGCGCGGAGCGTTTTTTGGTTTTGCT
CAAACATTTCGGCAGCGCATCGGCCGCGTTGAACGCGCCGGCGGACACCATTGCCAAGCTGGCCGCCCACAATCAGGCCG
CGACGGCTTGGCGCGACGGGGAAAAGCGCGCGCTGGCGCAAAAGGCGGCGGAAGCGGCGCTGCAATGGGAAACGCAGGCG
GGATGCCGTCTGATGCTGTTGGACGACGACGATTTTCCGACGATGCTGACCGAGGGCATCACGCCGCCGCCTTTGCTGTT
TTTGCGCGGCGATGTTGCGCTGCTGCACAAACCCGCCGTCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAAGGCTTTGAGTGAAAAAGGGATTCCCGTGGTTTCGGGCATGGCGGCGGGCATCGACACC
GCCGCACATCAGGGAGCGTTGCAGGCTTCGGGCGGCACGGTTACGGTTTGGGGAACGGGGATAGACCGCATCTATCCGCC
GTCCAACAGGCAACTGGCTTACGAGATCGCCGAACGCGGCCTGATTGTCAGCGAGTTTCCGCTCGACACGCGCCCGCTGG
CGGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGTGCGCCACACTGGTGGTGGAAGCGGCGGTGGAATCG
GGTTCGCTGATTACCGCGAAGCTGGCGGCGGAAATGGGGCGCGAGGTGATGGCAGTGCCCGGTTCGATTGACAATCCGCA
CAGCAAAGGCTGCCACAAGCTGATTAAAGAGGGCGCAAAACTGACGGAATGTTTGGACGATATTGTCCAAGAATGTCCGC
AGCTATTGCAAAACACGGCAAATCCATCATATTCTATAAATAAACGTCGGGAAAAGGTGCAAAACGAAACGCCGCCCCGC
CCCGAAACGCCCGCGCCCGTTGCGATGCCGTCTGAAAATGTGGCGCACCCGCTGCTTGACGCGATGGGTTACGACCCCGT
CCACCCCGATACGCTGGCGCAGCAGACGGGGCAGCCCGCCGCCGACGTTTACGCCGTGCTGATGGAATTAGAGCTTGACG
GCATCGTCGCTTCGTTGCCGGGCGGGCGTTATCAGAGAATTTCGTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (324-382)

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

3D structure

• AlphaFold DB: A0A220S544

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	71.93	100	0.74
dprA	Neisseria meningitidis MC58	71.93	100	0.74
dprA	Neisseria gonorrhoeae strain FA1090	71.537	100	0.732
dprA	Neisseria gonorrhoeae MS11	71.501	100	0.724
dprA	Vibrio cholerae strain A1552	39.386	100	0.397
dprA	Thermus thermophilus HB27	37.867	96.649	0.366
dprA	Glaesserella parasuis strain SC1401	37.666	97.165	0.366