Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   M6_RS00495 Genome accession   NC_006086
Coordinates   75042..75224 (+) Length   60 a.a.
NCBI ID   WP_011054856.1    Uniprot ID   A0A0H2UW47
Organism   Streptococcus pyogenes MGAS10394     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 70042..80224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6_RS00460 (M6_Spy0062) - 70431..71048 (+) 618 WP_011184056.1 DUF1366 domain-containing protein -
  M6_RS00465 (M6_Spy0063) - 71058..71330 (+) 273 WP_002986916.1 DUF7365 family protein -
  M6_RS00470 (M6_Spy0064) - 71327..71554 (+) 228 WP_003058873.1 phage holin -
  M6_RS00480 (M6_Spy0065) - 71670..72872 (+) 1203 WP_011184057.1 glucosaminidase domain-containing protein -
  M6_RS00485 (M6_Spy0066) - 73194..73709 (+) 516 WP_023077389.1 hypothetical protein -
  M6_RS00490 (M6_Spy0067) - 73823..74809 (-) 987 WP_011184058.1 DNA/RNA non-specific endonuclease -
  M6_RS00495 (M6_Spy0068) prx 75042..75224 (+) 183 WP_011054856.1 hypothetical protein Regulator
  M6_RS00500 (M6_Spy0069) plsX 75463..76470 (+) 1008 WP_011184059.1 phosphate acyltransferase PlsX -
  M6_RS00505 (M6_Spy0070) - 76463..76705 (+) 243 WP_002993445.1 phosphopantetheine-binding protein -
  M6_RS00510 (M6_Spy0071) purC 76857..77561 (+) 705 WP_027968831.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -

Sequence


Protein


Download         Length: 60 a.a.        Molecular weight: 6927.67 Da        Isoelectric Point: 3.9286

>NTDB_id=23743 M6_RS00495 WP_011054856.1 75042..75224(+) (prx) [Streptococcus pyogenes MGAS10394]
MLTYDEFKQAIDDGYITGDTVAIVRKNGQIFDYALPNEEVRNGEVVTYENVEEVLRELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=23743 M6_RS00495 WP_011054856.1 75042..75224(+) (prx) [Streptococcus pyogenes MGAS10394]
ATGCTAACATACGATGAGTTTAAGCAAGCTATTGATGACGGATATATCACAGGCGACACAGTGGCGATCGTGCGCAAAAA
CGGACAGATTTTTGATTATGCGTTGCCGAATGAAGAGGTAAGAAATGGGGAGGTTGTAACATACGAAAATGTGGAAGAAG
TGCTGAGGGAATTAGACAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2UW47

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1

  prx Streptococcus pyogenes MGAS8232

80

100

0.8

  prx Streptococcus pyogenes MGAS315

78.333

100

0.783

  prx Streptococcus pyogenes MGAS315

75

100

0.75

  prx Streptococcus pyogenes MGAS315

88.372

71.667

0.633

  prx Streptococcus pyogenes MGAS315

87.805

68.333

0.6

  prx Streptococcus pyogenes MGAS315

76.19

70

0.533


Multiple sequence alignment