Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   C6993_RS27730 Genome accession   NZ_CP027546
Coordinates   5150399..5151022 (+) Length   207 a.a.
NCBI ID   WP_000122253.1    Uniprot ID   A0A370V1H3
Organism   Escherichia coli strain 2013C-4187     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 5145399..5156022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6993_RS27705 ampG 5145791..5147266 (-) 1476 WP_000098425.1 muropeptide MFS transporter AmpG -
  C6993_RS27710 yajG 5147310..5147888 (-) 579 WP_001295326.1 lipoprotein -
  C6993_RS27715 bolA 5148193..5148510 (+) 318 WP_000973448.1 transcriptional regulator BolA -
  C6993_RS27725 tig 5148854..5150152 (+) 1299 WP_001198386.1 trigger factor -
  C6993_RS27730 clpP 5150399..5151022 (+) 624 WP_000122253.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  C6993_RS27735 clpX 5151148..5152422 (+) 1275 WP_000130305.1 ATP-dependent protease ATP-binding subunit ClpX Regulator
  C6993_RS27740 lon 5152610..5154964 (+) 2355 WP_001295325.1 endopeptidase La -
  C6993_RS27745 hupB 5155155..5155445 (+) 291 WP_254892905.1 nucleoid-associated protein HU-beta -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23186.65 Da        Isoelectric Point: 5.6032

>NTDB_id=235458 C6993_RS27730 WP_000122253.1 5150399..5151022(+) (clpP) [Escherichia coli strain 2013C-4187]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide


Download         Length: 624 bp        

>NTDB_id=235458 C6993_RS27730 WP_000122253.1 5150399..5151022(+) (clpP) [Escherichia coli strain 2013C-4187]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGCGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGACCACATGG
CTAACCTGATTGTGGCGCAGATGCTGTTCCTGGAAGCGGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCCCCA
GGCGGGGTGATCACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGCGCTTTCTTGTTGACCGCAGGGGCAAAAGGTAAACGTTTTTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAACCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCCGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(26-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A370V1H3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

69.792

92.754

0.647
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.617

90.821

0.623
  clpP Lactococcus lactis subsp. cremoris KW2

56.701

93.72

0.531
  clpP Streptococcus pneumoniae R6

55.155

93.72

0.517
  clpP Streptococcus pneumoniae TIGR4

55.155

93.72

0.517
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

55.155

93.72

0.517
  clpP Streptococcus pneumoniae Rx1

55.155

93.72

0.517
  clpP Streptococcus pneumoniae D39

55.155

93.72

0.517
  clpP Streptococcus thermophilus LMD-9

54.922

93.237

0.512
  clpP Streptococcus thermophilus LMG 18311

54.922

93.237

0.512
  clpP Streptococcus pyogenes JRS4

55.263

91.787

0.507
  clpP Streptococcus pyogenes MGAS315

55.263

91.787

0.507
  clpP Streptococcus mutans UA159

53.886

93.237

0.502

Multiple sequence alignment