Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   M6_RS06690 Genome accession   NC_006086
Coordinates   1331461..1331643 (-) Length   60 a.a.
NCBI ID   WP_011018104.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS10394     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1331461..1355794 1331461..1331643 within 0


Gene organization within MGE regions


Location: 1331461..1355794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6_RS06690 (M6_Spy1338) prx 1331461..1331643 (-) 183 WP_011018104.1 hypothetical protein Regulator
  M6_RS06695 (M6_Spy1339) sda 1331883..1332881 (+) 999 WP_032463908.1 streptodornase A -
  M6_RS06700 (M6_Spy1340) - 1333022..1333615 (-) 594 WP_003051628.1 GNAT family N-acetyltransferase -
  M6_RS06705 (M6_Spy1341) - 1333615..1333779 (-) 165 WP_021340366.1 hypothetical protein -
  M6_RS06710 (M6_Spy1342) - 1333928..1335133 (-) 1206 WP_011184795.1 glucosaminidase domain-containing protein -
  M6_RS06720 (M6_Spy1343) - 1335246..1335431 (-) 186 WP_011184796.1 holin -
  M6_RS06725 (M6_Spy1344) - 1335428..1335727 (-) 300 WP_011184797.1 hypothetical protein -
  M6_RS06730 (M6_Spy1345) - 1335738..1336355 (-) 618 WP_011018111.1 DUF1366 domain-containing protein -
  M6_RS06735 (M6_Spy1346) - 1336358..1336786 (-) 429 WP_011184798.1 DUF1617 family protein -
  M6_RS06740 (M6_Spy1347) - 1336798..1338813 (-) 2016 WP_011184799.1 gp58-like family protein -
  M6_RS06745 (M6_Spy1348) - 1338828..1339940 (-) 1113 WP_011184800.1 hyaluronoglucosaminidase -
  M6_RS06750 (M6_Spy1349) - 1339940..1342087 (-) 2148 WP_011184801.1 phage tail spike protein -
  M6_RS06755 (M6_Spy1350) - 1342084..1342800 (-) 717 WP_011018116.1 distal tail protein Dit -
  M6_RS06760 (M6_Spy1351) - 1342797..1346057 (-) 3261 WP_021340629.1 tape measure protein -
  M6_RS06765 (M6_Spy1352) - 1346047..1346628 (-) 582 WP_011018118.1 bacteriophage Gp15 family protein -
  M6_RS06770 (M6_Spy1353) - 1346632..1347066 (-) 435 WP_011018119.1 hypothetical protein -
  M6_RS06775 (M6_Spy1354) - 1347110..1347571 (-) 462 WP_011018120.1 phage tail tube protein -
  M6_RS06780 (M6_Spy1355) - 1347571..1347969 (-) 399 WP_011018121.1 minor capsid protein -
  M6_RS06785 (M6_Spy1356) - 1347966..1348322 (-) 357 WP_010922083.1 minor capsid protein -
  M6_RS06790 (M6_Spy1357) - 1348322..1348654 (-) 333 WP_010922082.1 minor capsid protein -
  M6_RS06795 (M6_Spy1358) - 1348644..1349060 (-) 417 WP_011018123.1 hypothetical protein -
  M6_RS06800 (M6_Spy1359) - 1349114..1349932 (-) 819 WP_010922080.1 N4-gp56 family major capsid protein -
  M6_RS06805 (M6_Spy1360) - 1349936..1350550 (-) 615 WP_010922079.1 hypothetical protein -
  M6_RS06810 (M6_Spy1361) - 1350676..1350942 (-) 267 WP_010922078.1 hypothetical protein -
  M6_RS06815 (M6_Spy1362) - 1351029..1351256 (-) 228 WP_010922077.1 hypothetical protein -
  M6_RS06820 (M6_Spy1363) - 1351256..1352749 (-) 1494 WP_011018124.1 phage minor capsid protein -
  M6_RS06825 (M6_Spy1364) - 1352754..1354256 (-) 1503 WP_011184804.1 phage portal protein -
  M6_RS06830 (M6_Spy1365) - 1354270..1355561 (-) 1292 Protein_1330 PBSX family phage terminase large subunit -
  M6_RS06835 (M6_Spy1366) - 1355564..1355794 (-) 231 WP_011184806.1 hypothetical protein -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6935.81 Da        Isoelectric Point: 3.9417

>NTDB_id=23461 M6_RS06690 WP_011018104.1 1331461..1331643(-) (prx) [Streptococcus pyogenes MGAS10394]
MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPHEEARNGEVVTEEVVEEVMVELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=23461 M6_RS06690 WP_011018104.1 1331461..1331643(-) (prx) [Streptococcus pyogenes MGAS10394]
ATGCTAACATACGACGAATTTAAGCAAGCGATTGACAATGGATATATCACAGCAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAAGAAGCGAGAAATGGAGAAGTTGTGACCGAGGAGGTAGTGGAAGAAG
TGATGGTGGAATTAGACAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

83.333

100

0.833
  prx Streptococcus pyogenes MGAS315

83.333

100

0.833
  prx Streptococcus pyogenes MGAS315

81.667

100

0.817
  prx Streptococcus pyogenes MGAS315

81.667

100

0.817
  prx Streptococcus pyogenes MGAS8232

80

100

0.8
  prx Streptococcus pyogenes MGAS315

76.667

100

0.767
  prx Streptococcus pyogenes MGAS315

93.023

71.667

0.667

Multiple sequence alignment