Detailed information NTG0234560

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: S100333_RS18270
• Genome accession: NZ_CP021892
• Coordinates: 3424746..3425339 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis subsp. subtilis strain SRCM100333
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3419746..3430339

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
S100333_RS18240 (S100333_03722)	aspP	3420720..3422282 (+)	1563	WP_003228228.1	aspartate/proton symporter AspP	-
S100333_RS18245 (S100333_03723)	-	3422377..3422961 (+)	585	WP_003228226.1	TetR family transcriptional regulator	-
S100333_RS18250 (S100333_03724)	psmA	3423043..3423378 (+)	336	WP_014480966.1	SMR family transporter	-
S100333_RS18255 (S100333_03725)	psmB	3423378..3423698 (+)	321	WP_014480967.1	QacE family quaternary ammonium compound efflux SMR transporter	-
S100333_RS18260 (S100333_03726)	yvdQ	3423734..3424242 (-)	509	Protein_3550	DUF3231 family protein	-
S100333_RS18270 (S100333_03728)	clpP	3424746..3425339 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
S100333_RS18275 (S100333_03729)	pgmB	3425402..3426076 (-)	675	WP_014480982.1	beta-phosphoglucomutase	-
S100333_RS18280 (S100333_03730)	malL	3426073..3427758 (-)	1686	WP_033881298.1	oligo-1,6-glucosidase	-
S100333_RS18285 (S100333_03731)	mdxK	3427751..3429913 (-)	2163	WP_088272523.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=234560 S100333_RS18270 WP_003228214.1 3424746..3425339(+) (clpP) [Bacillus subtilis subsp. subtilis strain SRCM100333]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=234560 S100333_RS18270 WP_003228214.1 3424746..3425339(+) (clpP) [Bacillus subtilis subsp. subtilis strain SRCM100333]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCATCAATGGGCGCTTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAACTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538