Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   BB159_RS09840 Genome accession   NZ_CP021868
Coordinates   1921119..1921871 (-) Length   250 a.a.
NCBI ID   WP_001019938.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain SG-M8     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1916119..1926871
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BB159_RS09815 (BB159_09815) - 1916996..1918150 (-) 1155 WP_000623428.1 ABC transporter permease subunit -
  BB159_RS09820 (BB159_09820) - 1918156..1919004 (-) 849 WP_000926590.1 ABC transporter ATP-binding protein -
  BB159_RS09825 (BB159_09825) - 1919073..1919246 (-) 174 WP_000683600.1 hypothetical protein -
  BB159_RS09830 (BB159_09830) - 1919535..1919699 (+) 165 Protein_1839 cysteine peptidase family C39 domain-containing protein -
  BB159_RS09835 (BB159_09835) - 1919788..1921122 (-) 1335 WP_001089366.1 sensor histidine kinase -
  BB159_RS09840 (BB159_09840) comE/blpR 1921119..1921871 (-) 753 WP_001019938.1 response regulator transcription factor Regulator
  BB159_RS09850 (BB159_09850) - 1922087..1922902 (-) 816 WP_001029870.1 endonuclease/exonuclease/phosphatase family protein -
  BB159_RS09855 (BB159_09855) - 1922956..1925139 (-) 2184 WP_000795065.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29451.04 Da        Isoelectric Point: 8.4441

>NTDB_id=234196 BB159_RS09840 WP_001019938.1 1921119..1921871(-) (comE/blpR) [Streptococcus agalactiae strain SG-M8]
MNIFILEDNFIQQARLERIIEEVKIRRSIHSKMVNTFEKPVQLLESICEKGMHNLYFLDIEIKNDEQRGLEVAKQIRQID
PYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEAFSRRIEDVLLYANNACSKNLLEDSFYFKSRYSQVQVPFNDILY
IETSLRSHRVVLYTAKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRSNKLIYLKNGSNCLISRNKIKDIMVV
IEENQRGRGI

Nucleotide


Download         Length: 753 bp        

>NTDB_id=234196 BB159_RS09840 WP_001019938.1 1921119..1921871(-) (comE/blpR) [Streptococcus agalactiae strain SG-M8]
GTGAATATTTTTATTTTAGAGGATAATTTTATTCAACAGGCACGTTTAGAGAGAATAATTGAGGAAGTTAAAATTAGGAG
AAGTATACACAGTAAAATGGTAAATACCTTTGAAAAACCAGTTCAATTATTGGAATCAATCTGTGAAAAAGGTATGCATA
ATTTATATTTCTTAGACATTGAAATAAAAAATGATGAGCAGAGGGGCTTAGAGGTCGCAAAACAAATTAGACAAATTGAT
CCTTATGCTCAGATTGTTTTTGTTACAACTCATTCGGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGCATTTAGCAGAAGGATTGAAGACGTTTTACTATATGCTAATAATGCTTGCA
GTAAAAACTTACTAGAAGATTCTTTTTATTTTAAATCACGCTATAGTCAAGTACAAGTACCTTTTAACGATATCCTTTAT
ATAGAAACGTCATTAAGGTCACATAGAGTTGTCCTTTATACTGCAAAAGACAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTGAATATTTTTAAAGTGGATA
GGTCAAATAAACTAATCTATTTAAAAAATGGTTCGAATTGTTTGATTTCTCGTAATAAAATAAAAGATATTATGGTAGTA
ATAGAGGAAAATCAAAGAGGTAGAGGAATATGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-238)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

99.6

0.524
  comE/comE1 Streptococcus equinus JB1

42.678

95.6

0.408
  comE Streptococcus pneumoniae D39

38.866

98.8

0.384
  comE Streptococcus pneumoniae R6

38.866

98.8

0.384
  comE Streptococcus pneumoniae TIGR4

38.866

98.8

0.384
  comE Streptococcus mitis SK321

38.866

98.8

0.384
  comE Streptococcus mitis NCTC 12261

38.866

98.8

0.384
  comE Streptococcus pneumoniae Rx1

38.866

98.8

0.384
  comE Streptococcus infantis strain Atu-4

36.8

100

0.368

Multiple sequence alignment