Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AYN27_RS10495 Genome accession   NZ_CP027380
Coordinates   1905789..1906445 (+) Length   218 a.a.
NCBI ID   WP_000611339.1    Uniprot ID   -
Organism   Escherichia coli strain 2013C-3250     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1900789..1911445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AYN27_RS10470 dcyD 1901669..1902655 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  AYN27_RS10475 tcyL 1902670..1903338 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  AYN27_RS10480 tcyN 1903335..1904087 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AYN27_RS10485 sdiA 1904317..1905039 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  AYN27_RS10490 yecF 1905106..1905330 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  AYN27_RS30940 yecU 1905317..1905493 (-) 177 WP_000590347.1 protein YecU -
  AYN27_RS32245 - 1905576..1905647 (-) 72 Protein_1962 transcriptional regulator -
  AYN27_RS10495 letA 1905789..1906445 (+) 657 WP_000611339.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AYN27_RS10500 uvrC 1906442..1908274 (+) 1833 WP_001283425.1 excinuclease ABC subunit UvrC Machinery gene
  AYN27_RS10505 pgsA 1908331..1908879 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AYN27_RS10525 yecA 1909529..1910194 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23920.71 Da        Isoelectric Point: 6.9614

>NTDB_id=233245 AYN27_RS10495 WP_000611339.1 1905789..1906445(+) (letA) [Escherichia coli strain 2013C-3250]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEVSCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=233245 AYN27_RS10495 WP_000611339.1 1905789..1906445(+) (letA) [Escherichia coli strain 2013C-3250]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGTATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment