Detailed information NTG0231606

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: CCD86_RS09960
• Genome accession: NZ_CP021518
• Coordinates: 1763031..1764218 (-)
• Length: 395 a.a.
• NCBI ID: WP_002260362.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain 12-176
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1758031..1769218

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CCD86_RS09935 (CCD86_10075)	-	1758324..1758701 (-)	378	WP_002233408.1	helix-turn-helix transcriptional regulator	-
CCD86_RS09940 (CCD86_10080)	-	1758820..1759371 (+)	552	WP_002230190.1	hypothetical protein	-
CCD86_RS09945 (CCD86_10085)	-	1759391..1760086 (+)	696	WP_002233407.1	hypothetical protein	-
CCD86_RS09950 (CCD86_10090)	topA	1760159..1762465 (-)	2307	WP_002234458.1	type I DNA topoisomerase	-
CCD86_RS09955 (CCD86_10095)	-	1762544..1763005 (-)	462	WP_002215351.1	DUF494 domain-containing protein	-
CCD86_RS09960 (CCD86_10100)	dprA	1763031..1764218 (-)	1188	WP_002260362.1	DNA-processing protein DprA	Machinery gene
CCD86_RS09965 (CCD86_10105)	-	1764309..1765586 (-)	1278	WP_002260361.1	sigma-54 dependent transcriptional regulator	-
CCD86_RS09970 (CCD86_10110)	-	1765579..1767696 (-)	2118	WP_002260360.1	PAS domain-containing sensor histidine kinase	-
CCD86_RS09975 (CCD86_10115)	-	1767696..1768295 (-)	600	WP_002216221.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41925.01 Da
• Isoelectric Point: 6.3949

>NTDB_id=231606 CCD86_RS09960 WP_002260362.1 1763031..1764218(-) (dprA) [Neisseria meningitidis strain 12-176]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVAPAVRHKQAAEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGEKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=231606 CCD86_RS09960 WP_002260362.1 1763031..1764218(-) (dprA) [Neisseria meningitidis strain 12-176]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCCGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGAGAGAAAGGCATTCCCGTTGTGTCGGGTATGGCTTCGGGCATCGATACC
GCCGCCCATCAGGGTGCGTTGCAGGCGGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGACTGATTGTCAGCGAGTTCCCCATCGGCACGCGCCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTTGAAGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCTTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGCTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAATTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

• DprA winged helix domain (DprA_WH) (341-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	97.468	100	0.975
dprA	Neisseria gonorrhoeae strain FA1090	97.215	100	0.972
dprA	Neisseria meningitidis strain C311	90.176	100	0.906
dprA	Neisseria meningitidis MC58	90.176	100	0.906
dprA	Glaesserella parasuis strain SC1401	40.209	96.962	0.39
dprA	Vibrio cholerae strain A1552	38.035	100	0.382