Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CA925_RS07500 Genome accession   NZ_CP021266
Coordinates   1646247..1647467 (+) Length   406 a.a.
NCBI ID   WP_027225016.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila strain Knoxville     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1641247..1652467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA925_RS07480 - 1642394..1642963 (-) 570 WP_014843845.1 hypoxanthine-guanine phosphoribosyltransferase -
  CA925_RS07485 - 1643006..1643332 (-) 327 WP_011213802.1 DUF1820 family protein -
  CA925_RS07490 - 1643515..1644258 (-) 744 WP_014843846.1 methyltransferase domain-containing protein -
  CA925_RS07495 pilB 1644517..1646241 (+) 1725 WP_014843847.1 type IV-A pilus assembly ATPase PilB Machinery gene
  CA925_RS07500 pilC 1646247..1647467 (+) 1221 WP_027225016.1 type II secretion system F family protein Machinery gene
  CA925_RS07505 pilD 1647513..1648376 (+) 864 WP_027225017.1 A24 family peptidase Machinery gene
  CA925_RS07510 - 1648390..1649595 (-) 1206 WP_014843849.1 cyclic nucleotide-binding domain-containing protein -
  CA925_RS07515 - 1649703..1650296 (-) 594 WP_011213808.1 hypothetical protein -
  CA925_RS07520 - 1650312..1650767 (-) 456 WP_011213809.1 hypothetical protein -
  CA925_RS07525 - 1650901..1651716 (+) 816 WP_010947257.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44731.97 Da        Isoelectric Point: 9.6052

>NTDB_id=229380 CA925_RS07500 WP_027225016.1 1646247..1647467(+) (pilC) [Legionella pneumophila subsp. pneumophila strain Knoxville]
MDKNSPPLLTFHYQGINKAGQKMEGDIQARSLAIAKADLRKQGIVTNKVVKKRKPLFDRKNKKITQADITVFSRQLATMI
ESGIPLVQAFDIVAKGQSNKRLKDLIETIKHDIETGLTLAESLIKHPLYFNELFCNLVDAGEKSGSLDIMLDKVATYKEK
IEIIKKKIKKALTYPIAVMVVALLVTAGLLIYVVPQFESLFKGFGADLPAMTRAVITMSEFMQAYWYIIFGALGGIVYSF
FYAKNHSLEFAQIIDRVMLKFPVIGPILEKAAIARFARTLSITFAAGLPLVEALKSVAGATGNIIYAKATDKIREEVATG
QQMFIAMENTHLFPNMVIQMVAIGEESGALEKMLSKVADFYEEEVNNAVDALSSLLEPIIMSILGILVGGLVVAMYLPIF
KLGSAV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=229380 CA925_RS07500 WP_027225016.1 1646247..1647467(+) (pilC) [Legionella pneumophila subsp. pneumophila strain Knoxville]
ATGGATAAAAATAGCCCACCCCTATTAACCTTTCATTATCAAGGCATTAATAAAGCCGGTCAAAAAATGGAGGGTGATAT
TCAAGCCAGAAGCTTGGCAATAGCTAAAGCTGATTTGCGTAAGCAGGGGATTGTTACCAATAAAGTAGTAAAAAAAAGAA
AACCTTTGTTTGATAGAAAAAATAAAAAAATCACACAAGCAGATATTACTGTATTTAGCCGCCAATTAGCGACGATGATC
GAGTCTGGAATACCATTAGTGCAAGCGTTTGATATTGTTGCCAAAGGACAAAGCAATAAAAGACTTAAAGACTTAATAGA
AACAATTAAGCACGATATCGAAACGGGGCTAACGCTAGCAGAATCCTTAATTAAACATCCACTCTATTTTAATGAATTAT
TTTGTAATCTTGTCGATGCAGGTGAAAAATCAGGCTCATTAGATATCATGCTTGACAAGGTTGCAACGTATAAAGAAAAA
ATTGAAATCATAAAAAAGAAAATAAAAAAAGCTCTCACTTATCCAATTGCTGTTATGGTTGTCGCACTTTTGGTTACTGC
GGGATTATTAATCTATGTGGTTCCTCAATTTGAATCATTGTTTAAAGGATTTGGAGCTGACTTGCCAGCGATGACTAGAG
CTGTGATCACTATGTCTGAATTTATGCAGGCTTATTGGTATATTATTTTTGGAGCTTTGGGTGGGATTGTCTATAGCTTT
TTTTATGCTAAAAATCACTCTTTGGAATTTGCTCAAATTATTGACAGAGTGATGCTAAAATTCCCTGTAATTGGCCCTAT
TTTAGAGAAAGCAGCAATTGCTCGATTTGCGAGGACATTATCCATTACTTTTGCTGCTGGATTACCCCTGGTTGAAGCAT
TGAAATCTGTAGCTGGAGCGACCGGGAATATTATTTATGCCAAGGCGACTGATAAAATCAGGGAAGAAGTTGCAACAGGA
CAGCAAATGTTTATTGCTATGGAAAACACTCATTTATTTCCGAATATGGTAATTCAAATGGTAGCAATTGGTGAGGAATC
AGGTGCCCTTGAAAAAATGTTAAGCAAAGTAGCTGATTTTTATGAGGAAGAAGTAAATAATGCTGTAGATGCCCTAAGTA
GTTTATTGGAGCCGATAATTATGTCAATATTGGGTATACTGGTTGGGGGATTGGTGGTGGCTATGTATTTACCTATTTTC
AAACTGGGTTCTGCTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

99.261

100

0.993
  pilC Pseudomonas stutzeri DSM 10701

54.208

99.507

0.539
  pilC Acinetobacter baumannii D1279779

53.333

99.754

0.532
  pilC Acinetobacter baylyi ADP1

52.84

99.754

0.527
  pilG Neisseria meningitidis 44/76-A

45.088

97.783

0.441
  pilG Neisseria gonorrhoeae MS11

44.836

97.783

0.438
  pilC Vibrio cholerae strain A1552

42.25

98.522

0.416
  pilC Vibrio campbellii strain DS40M4

39.163

100

0.392

Multiple sequence alignment