Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AM456_RS17240 Genome accession   NZ_CP026755
Coordinates   3216336..3216995 (+) Length   219 a.a.
NCBI ID   WP_033560344.1    Uniprot ID   -
Organism   Escherichia coli strain AR_0077     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3211336..3221995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM456_RS17225 (AM456_17245) ygiS 3213541..3215148 (-) 1608 WP_001361224.1 ABC transporter substrate-binding protein -
  AM456_RS17230 (AM456_17250) ygiV 3215257..3215739 (-) 483 WP_000183492.1 GyrI-like domain-containing protein -
  AM456_RS17235 (AM456_17255) ygiW 3215792..3216184 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  AM456_RS17240 (AM456_17260) ciaR 3216336..3216995 (+) 660 WP_033560344.1 quorum sensing response regulator transcription factor QseB Regulator
  AM456_RS17245 (AM456_17265) qseC 3216992..3218341 (+) 1350 WP_094029925.1 quorum sensing histidine kinase QseC -
  AM456_RS17250 (AM456_17270) mdaB 3218451..3219032 (+) 582 WP_032330190.1 NADPH:quinone oxidoreductase MdaB -
  AM456_RS17255 (AM456_17275) ygiN 3219063..3219377 (+) 315 WP_000633737.1 putative quinol monooxygenase -
  AM456_RS17260 (AM456_17280) - 3219422..3220309 (-) 888 WP_000614945.1 MurR/RpiR family transcriptional regulator -
  AM456_RS17265 (AM456_17285) - 3220306..3221253 (-) 948 WP_104888963.1 iron-siderophore ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24673.60 Da        Isoelectric Point: 6.9850

>NTDB_id=228566 AM456_RS17240 WP_033560344.1 3216336..3216995(+) (ciaR) [Escherichia coli strain AR_0077]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVVLDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=228566 AM456_RS17240 WP_033560344.1 3216336..3216995(+) (ciaR) [Escherichia coli strain AR_0077]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGGTCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTTTTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment