Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   GBS_RS04105 Genome accession   NC_004368
Coordinates   759044..759754 (+) Length   236 a.a.
NCBI ID   WP_000722052.1    Uniprot ID   X5K3L1
Organism   Streptococcus agalactiae NEM316     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 754044..764754
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBS_RS04075 (gbs0735) - 754566..755150 (+) 585 WP_000666008.1 hypothetical protein -
  GBS_RS04080 (gbs0736) - 755289..756107 (+) 819 WP_001222610.1 ParA family protein -
  GBS_RS04085 (gbs0737) - 756104..756382 (+) 279 WP_000131727.1 hypothetical protein -
  GBS_RS04090 (gbs0738) - 756395..756778 (+) 384 WP_000323828.1 replication initiator protein A -
  GBS_RS04095 (gbs0739) - 756783..757094 (+) 312 WP_000583310.1 hypothetical protein -
  GBS_RS04100 (gbs0740) - 757228..758556 (+) 1329 WP_000151682.1 ISLre2 family transposase -
  GBS_RS04105 (gbs0741) vicR 759044..759754 (+) 711 WP_000722052.1 response regulator YycF Regulator
  GBS_RS04110 (gbs0742) vicK 759747..761096 (+) 1350 WP_001065469.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GBS_RS04115 (gbs0743) vicX 761100..761909 (+) 810 WP_001289499.1 MBL fold metallo-hydrolase Regulator
  GBS_RS04120 (gbs0744) - 761912..762280 (+) 369 WP_000719384.1 YbaN family protein -
  GBS_RS04125 (gbs0745) rnc 762456..763142 (+) 687 WP_000661526.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27063.90 Da        Isoelectric Point: 4.8246

>NTDB_id=22457 GBS_RS04105 WP_000722052.1 759044..759754(+) (vicR) [Streptococcus agalactiae NEM316]
MKKILIVDDEKPISDIIKFNLTKEGYETATAFDGREALVQYAEFQPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEESAQNASSDITIGELQILPDAFIAKKRGEEIE
LTHREFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=22457 GBS_RS04105 WP_000722052.1 759044..759754(+) (vicR) [Streptococcus agalactiae NEM316]
ATGAAAAAAATACTTATCGTTGATGATGAAAAACCAATTTCAGATATTATCAAATTTAATTTAACCAAAGAAGGATATGA
GACGGCGACAGCTTTCGATGGCCGTGAAGCTTTAGTACAATATGCAGAATTTCAACCAGATTTAATCATTTTGGATTTAA
TGCTCCCTGAACTAGATGGTTTAGAAGTGGCTAAAGAAGTTCGTAAAACCAGCCATATTCCTATTATTATGCTTTCTGCA
AAAGATAGTGAGTTTGACAAAGTCATTGGTTTAGAAATCGGTGCAGATGATTATGTTACTAAACCTTTTTCAAATCGTGA
ACTTTTGGCACGGGTCAAAGCACATTTACGACGTACTGAAAATATTGAAACAGCTGTAGCAGAAGAAAGTGCTCAAAATG
CTTCTTCGGATATTACTATTGGTGAGTTGCAAATTTTACCAGACGCCTTTATTGCTAAGAAACGTGGCGAAGAAATTGAA
TTAACGCACCGAGAATTTGAATTACTTCACCATTTAGCGACACATATCGGACAAGTCATGACACGCGAACATTTATTGGA
AACAGTTTGGGGATATGATTATTTTGGAGATGTCCGTACAGTTGATGTGACGGTGAGACGTTTACGTGAAAAGATTGAAG
ATACTCCTGGTCGTCCAGAATATATTTTGACTCGACGTGGTGTAGGTTATTACATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X5K3L1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

77.778

99.153

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.983

98.305

0.462
  covR Streptococcus salivarius strain HSISS4

44.635

98.729

0.441
  scnR Streptococcus mutans UA159

38.559

100

0.386

Multiple sequence alignment