Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   C2E46_RS04360 Genome accession   NZ_CP026082
Coordinates   835714..836367 (+) Length   217 a.a.
NCBI ID   WP_161501833.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain YZ1605     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 830714..841367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS04335 (C2E46_04455) - 830885..831715 (+) 831 WP_000735511.1 MetQ/NlpA family ABC transporter substrate-binding protein -
  C2E46_RS04340 (C2E46_04460) - 831949..833535 (+) 1587 WP_161501832.1 DEAD/DEAH box helicase -
  C2E46_RS04345 (C2E46_04465) - 833717..833983 (-) 267 WP_000598734.1 GIY-YIG nuclease family protein -
  C2E46_RS04350 (C2E46_04470) - 833976..834740 (-) 765 WP_000611115.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  C2E46_RS04355 (C2E46_04475) - 834875..835615 (+) 741 WP_000500220.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  C2E46_RS04360 (C2E46_04480) comEA/celA/cilE 835714..836367 (+) 654 WP_161501833.1 helix-hairpin-helix domain-containing protein Machinery gene
  C2E46_RS04365 (C2E46_04485) comEC/celB 836351..838588 (+) 2238 WP_000939913.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  C2E46_RS04370 (C2E46_04490) - 838714..839523 (+) 810 WP_000153219.1 Cof-type HAD-IIB family hydrolase -
  C2E46_RS04375 (C2E46_04495) - 839534..840478 (+) 945 WP_000200832.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23756.05 Da        Isoelectric Point: 8.3966

>NTDB_id=224495 C2E46_RS04360 WP_161501833.1 835714..836367(+) (comEA/celA/cilE) [Streptococcus agalactiae strain YZ1605]
MFEIVLEKIKSHKWETTGIIVGLLLFGILGLNHFGTHYKDDDLNINLEKKVSTITEKKVPMISHVKDKVSNQVTVDVKGA
VNHPGVYSLPSQSRVTDAIKRAGGLSNLADSKSVNLAQKLQDETVVYVAQKGEKITVVEEEKENNIATQGNSKGKINLNK
ADLSSLQTISGVGAKRGQDILDYRDSQGGFKTIDDLKNVSGIGEKTLEKLRQDVTID

Nucleotide


Download         Length: 654 bp        

>NTDB_id=224495 C2E46_RS04360 WP_161501833.1 835714..836367(+) (comEA/celA/cilE) [Streptococcus agalactiae strain YZ1605]
ATGTTTGAAATAGTATTGGAAAAAATTAAATCGCATAAATGGGAGACAACAGGAATTATTGTAGGACTCTTATTATTTGG
AATTTTGGGTTTAAATCATTTTGGCACTCATTATAAAGACGACGATTTAAATATTAATTTAGAGAAAAAAGTATCAACTA
TAACAGAAAAAAAGGTACCAATGATTAGTCACGTCAAAGATAAAGTATCTAATCAAGTAACGGTTGACGTAAAAGGGGCA
GTCAATCATCCAGGTGTTTATAGTTTGCCTTCTCAAAGTCGTGTAACAGATGCGATTAAGCGTGCAGGTGGACTAAGCAA
TCTCGCTGATAGTAAATCCGTTAATCTAGCACAGAAATTACAAGATGAGACGGTTGTCTATGTTGCTCAAAAAGGTGAAA
AAATAACTGTTGTGGAAGAGGAGAAAGAAAATAATATCGCCACTCAGGGAAATAGTAAGGGGAAAATTAATCTTAATAAA
GCAGATTTATCAAGTCTTCAGACCATATCAGGCGTTGGAGCTAAAAGAGGTCAAGATATTTTAGATTATCGTGATAGTCA
AGGTGGTTTTAAAACTATTGATGACCTCAAAAACGTATCAGGTATTGGTGAGAAAACACTAGAAAAATTACGTCAAGATG
TTACAATTGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(75-128)

Helix-hairpin-helix motif (HHH_3)

(153-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

44.144

100

0.452
  comEA/celA/cilE Streptococcus mitis SK321

43.694

100

0.447
  comEA/celA/cilE Streptococcus pneumoniae Rx1

43.243

100

0.442
  comEA/celA/cilE Streptococcus pneumoniae D39

43.243

100

0.442
  comEA/celA/cilE Streptococcus pneumoniae R6

43.243

100

0.442
  comEA/celA/cilE Streptococcus mitis NCTC 12261

42.793

100

0.438
  comEA Lactococcus lactis subsp. cremoris KW2

38.117

100

0.392
  comEA Streptococcus thermophilus LMD-9

53.247

70.968

0.378

Multiple sequence alignment