Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilU   Type   Machinery gene
Locus tag   NMA_RS01140 Genome accession   NC_003116
Coordinates   204160..205386 (+) Length   408 a.a.
NCBI ID   WP_010981061.1    Uniprot ID   -
Organism   Neisseria meningitidis Z2491     
Function   mediate the depolymerization of the type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 199160..210386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA_RS01115 (NMA0213) dksA 200338..200754 (-) 417 WP_002231430.1 RNA polymerase-binding protein DksA -
  NMA_RS01120 (NMA0215) proC 200901..201692 (-) 792 WP_002247189.1 pyrroline-5-carboxylate reductase -
  NMA_RS01125 (NMA0216) - 201741..202148 (-) 408 WP_002221801.1 hypothetical protein -
  NMA_RS01130 (NMA0217) - 202148..202834 (-) 687 WP_002247191.1 YggS family pyridoxal phosphate-dependent enzyme -
  NMA_RS01135 (NMA0218) pilT 202954..203997 (+) 1044 WP_002215258.1 type IV pilus twitching motility protein PilT Machinery gene
  NMA_RS01140 (NMA0219) pilU 204160..205386 (+) 1227 WP_010981061.1 PilT/PilU family type 4a pilus ATPase Machinery gene
  NMA_RS01145 (NMA0220) yccS 205672..207822 (+) 2151 WP_010981062.1 YccS family putative transporter -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45620.19 Da        Isoelectric Point: 6.9640

>NTDB_id=22394 NMA_RS01140 WP_010981061.1 204160..205386(+) (pilU) [Neisseria meningitidis Z2491]
MNTDNLHDILDEMVQVYSQKKQSRSETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRGGTRYRANAYHSQGSAGLVLRRINHVIPQMQELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPSHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSSDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKQDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLVS

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=22394 NMA_RS01140 WP_010981061.1 204160..205386(+) (pilU) [Neisseria meningitidis Z2491]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAATGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCGCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAGTCGCGCGGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCAGGAATTGGGCCTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCAGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAGTCCTCCGACGTGGTCTGCATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATCGACATCGCCC
TCAACCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAACAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGATCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCGTTTCCTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(49-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilU Acinetobacter baylyi ADP1

44.321

88.48

0.392
  pilU Pseudomonas stutzeri DSM 10701

44.663

87.255

0.39
  pilU Vibrio cholerae strain A1552

45.833

82.353

0.377

Multiple sequence alignment