Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6J88_RS15785 Genome accession   NZ_CP020452
Coordinates   372964..373254 (-) Length   96 a.a.
NCBI ID   WP_080613446.1    Uniprot ID   -
Organism   Neisseria mucosa strain FDAARGOS_260     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 365446..372142 372964..373254 flank 822


Gene organization within MGE regions


Location: 365446..373254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J88_RS15740 (A6J88_01730) - 365446..365772 (+) 327 Protein_331 transposase -
  A6J88_RS15745 (A6J88_01735) - 365817..366824 (+) 1008 WP_080613443.1 IS5 family transposase -
  A6J88_RS15750 (A6J88_01745) - 367026..367832 (-) 807 WP_080613444.1 integrase core domain-containing protein -
  A6J88_RS15755 (A6J88_01750) - 367874..368530 (+) 657 Protein_334 IS30 family transposase -
  A6J88_RS15760 (A6J88_01755) - 368702..370015 (+) 1314 WP_060974820.1 NCS2 family permease -
  A6J88_RS15770 (A6J88_01760) - 370183..371093 (+) 911 WP_240593995.1 IS630 family transposase -
  A6J88_RS15775 (A6J88_01765) - 371135..372142 (-) 1008 WP_080613445.1 IS5 family transposase -
  A6J88_RS15780 (A6J88_01770) comP 372326..372790 (-) 465 WP_060975682.1 type IV pilin protein Machinery gene
  A6J88_RS15785 (A6J88_01775) comE 372964..373254 (-) 291 WP_080613446.1 ComEA family DNA-binding protein Machinery gene

Sequence

Protein


Download         Length: 96 a.a.        Molecular weight: 10032.75 Da        Isoelectric Point: 10.5400

>NTDB_id=223289 A6J88_RS15785 WP_080613446.1 372964..373254(-) (comE) [Neisseria mucosa strain FDAARGOS_260]
MKKFLFAALSVLTASLSLAAVNINTASPSELEALPGIGPAKAKAIVDYRQQHGAFKSVEELKNVKGIGEGIFSKLKAEAT
VAPAPANIKAKNTIQK

Nucleotide


Download         Length: 291 bp        

>NTDB_id=223289 A6J88_RS15785 WP_080613446.1 372964..373254(-) (comE) [Neisseria mucosa strain FDAARGOS_260]
ATGAAAAAATTCCTCTTTGCCGCACTCTCCGTTCTGACCGCCTCGCTGTCGCTGGCAGCCGTCAACATCAATACTGCTTC
CCCGTCCGAATTGGAAGCCCTGCCCGGCATCGGCCCGGCCAAAGCGAAAGCCATTGTGGACTACCGCCAGCAGCACGGTG
CCTTCAAATCAGTGGAAGAGCTCAAAAACGTTAAAGGCATCGGCGAGGGTATCTTCTCCAAACTGAAGGCCGAAGCAACC
GTCGCGCCCGCACCTGCAAACATAAAAGCTAAAAACACTATTCAAAAGTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(20-77)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

61.628

89.583

0.552
  comE Neisseria gonorrhoeae MS11

61.628

89.583

0.552
  comE Neisseria gonorrhoeae MS11

61.628

89.583

0.552
  comE Neisseria gonorrhoeae MS11

61.628

89.583

0.552
  Cj0011c Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

53.086

84.375

0.448
  comEA Vibrio parahaemolyticus RIMD 2210633

46.512

89.583

0.417
  comEA Staphylococcus aureus N315

57.377

63.542

0.365
  comEA Staphylococcus aureus MW2

57.377

63.542

0.365

Multiple sequence alignment