Detailed information NTG0222917

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: A6J31_RS11105
• Genome accession: NZ_CP020431
• Coordinates: 2156711..2157301 (+)
• Length: 196 a.a.
• NCBI ID: WP_080611198.1
• Uniprot ID: A0A1V0GGB3
• Organism: Streptococcus sp. FDAARGOS_192
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2151711..2162301

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J31_RS11095 (A6J31_11035)	-	2154440..2155689 (-)	1250	Protein_1918	ISL3 family transposase	-
A6J31_RS11100 (A6J31_11040)	upp	2155907..2156536 (+)	630	WP_002883819.1	uracil phosphoribosyltransferase	-
A6J31_RS11105 (A6J31_11045)	clpP	2156711..2157301 (+)	591	WP_080611198.1	ATP-dependent Clp protease proteolytic subunit	Regulator
A6J31_RS11110 (A6J31_11050)	-	2157387..2157836 (+)	450	WP_080611199.1	YlbF family regulator	-
A6J31_RS11115 (A6J31_11055)	-	2157829..2158110 (+)	282	WP_014633923.1	DUF2129 domain-containing protein	-
A6J31_RS11120 (A6J31_11060)	-	2158265..2159440 (+)	1176	WP_073949256.1	ABC transporter substrate-binding protein	-
A6J31_RS11125 (A6J31_11065)	-	2159484..2160368 (+)	885	WP_002890014.1	branched-chain amino acid ABC transporter permease	-
A6J31_RS11130 (A6J31_11070)	-	2160372..2161322 (+)	951	WP_080611201.1	branched-chain amino acid ABC transporter permease	-
A6J31_RS11135 (A6J31_11075)	-	2161325..2162089 (+)	765	WP_002883723.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21542.58 Da
• Isoelectric Point: 4.5831

>NTDB_id=222917 A6J31_RS11105 WP_080611198.1 2156711..2157301(+) (clpP) [Streptococcus sp. FDAARGOS_192]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEQILADNSGH
PIEKVHVDAERDNWMSAQETLEYGFIDEIMANNQLK

Nucleotide

• Length: 591 bp

>NTDB_id=222917 A6J31_RS11105 WP_080611198.1 2156711..2157301(+) (clpP) [Streptococcus sp. FDAARGOS_192]
ATGATTCCTGTAGTAATTGAACAAACATCGCGCGGTGAGCGTTCTTATGATATTTACTCACGTTTGCTCAAGGATCGTAT
CATCATGTTAACAGGTCCTGTTGAAGATAATATGGCAAACTCAATTATCGCCCAACTCTTGTTCTTGGATGCTCAAGACA
ACACAAAAGATATCTATCTTTATGTTAATACACCAGGTGGATCAGTTTCGGCAGGTCTTGCCATTGTTGATACAATGAAC
TTCATCAAGTCTGATGTTCAGACTATCGTTATGGGGATGGCAGCATCTATGGGAACAATTATCGCTTCAAGCGGTACCAA
AGGTAAACGTTTCATGTTGCCAAATGCTGAGTACATGATTCACCAACCAATGGGTGGTACTGGTGGTGGTACGCAACAAA
CAGACATGGCTATCGCAGCTGAACATTTGCTCAAAACGCGTAATAACTTGGAGCAAATCTTGGCGGATAATTCTGGACAT
CCAATTGAAAAAGTTCATGTAGACGCTGAACGTGACAATTGGATGAGTGCCCAAGAAACGCTTGAATATGGCTTTATCGA
TGAAATCATGGCTAATAACCAATTAAAATAG

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A1V0GGB3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus thermophilus LMG 18311	98.469	100	0.985
clpP	Streptococcus thermophilus LMD-9	98.469	100	0.985
clpP	Streptococcus pneumoniae D39	93.333	99.49	0.929
clpP	Streptococcus pneumoniae R6	93.333	99.49	0.929
clpP	Streptococcus pneumoniae TIGR4	93.333	99.49	0.929
clpP	Streptococcus pneumoniae Rx1	93.333	99.49	0.929
clpP	Streptococcus pyogenes MGAS315	90.306	100	0.903
clpP	Streptococcus pyogenes JRS4	90.306	100	0.903
clpP	Streptococcus mutans UA159	88.265	100	0.883
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.755	100	0.878
clpP	Lactococcus lactis subsp. cremoris KW2	87.245	100	0.872
clpP	Bacillus subtilis subsp. subtilis str. 168	57.653	100	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	98.469	0.566