Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   A6J31_RS10765 Genome accession   NZ_CP020431
Coordinates   2083340..2084239 (+) Length   299 a.a.
NCBI ID   WP_073687415.1    Uniprot ID   A0A1V0GG23
Organism   Streptococcus sp. FDAARGOS_192     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2078340..2089239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS10745 (A6J31_10685) trkA 2079504..2080853 (-) 1350 WP_014633874.1 Trk system potassium transporter TrkA -
  A6J31_RS10750 (A6J31_10690) - 2081131..2081640 (+) 510 WP_070655612.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  A6J31_RS10755 (A6J31_10695) - 2081949..2082506 (+) 558 WP_070849311.1 ECF transporter S component -
  A6J31_RS10760 (A6J31_10700) - 2082509..2083159 (+) 651 WP_073687416.1 phosphatase PAP2 family protein -
  A6J31_RS10765 (A6J31_10705) comR 2083340..2084239 (+) 900 WP_073687415.1 helix-turn-helix transcriptional regulator Regulator
  A6J31_RS10770 (A6J31_10710) comA 2084414..2086510 (+) 2097 WP_080611183.1 peptide cleavage/export ABC transporter Regulator
  A6J31_RS10775 (A6J31_10715) - 2086635..2086967 (+) 333 WP_014633880.1 DUF805 domain-containing protein -
  A6J31_RS10780 (A6J31_10720) - 2087019..2088410 (-) 1392 WP_048790673.1 DUF4153 domain-containing protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35191.78 Da        Isoelectric Point: 5.8538

>NTDB_id=222913 A6J31_RS10765 WP_073687415.1 2083340..2084239(+) (comR) [Streptococcus sp. FDAARGOS_192]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDKLSYIAKRLGKNMADLLDHDNITIPDEYYE
MKNRLIKFPTYRNPERIKAKLALIEEVYEKFFELLPEEELLTLDILENILSFTNWEESPKVEEIYEDLFEQVKRKKKFLT
NDLLVIDYYFFHLYGRKQFDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QFYSYKPSVFVLKAKYELLHKGNKKKAAENYDKAIMFASVLEDSVLEESIRAGKAADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=222913 A6J31_RS10765 WP_073687415.1 2083340..2084239(+) (comR) [Streptococcus sp. FDAARGOS_192]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGTCAGCAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTGCGTCAGTTAATTCGCATTGAAAAAGGGGAGTCGCTCCCGTCTTTGGATAAATTATCTT
ATATTGCAAAACGTCTAGGAAAAAATATGGCCGATTTATTGGATCATGACAATATTACCATTCCTGACGAATATTATGAG
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAATCCAGAAAGAATAAAGGCTAAACTTGCCTTAATTGAGGAAGT
CTATGAGAAATTCTTTGAACTTCTGCCAGAAGAAGAGTTGTTAACTCTAGATATTTTGGAAAATATTTTGAGTTTTACTA
ATTGGGAGGAGAGCCCAAAGGTTGAAGAAATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAAGAAATTCTTAACT
AACGATTTATTAGTTATTGACTATTATTTCTTCCATCTCTATGGAAGAAAACAGTTTGACAAAAAACTTTTTGAAAGGAT
TGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGACGATGTCTATAATATTGTTTTATTTAATGATTTGATGGCTATCG
CTGCTTTGAAGATTTTTCACAATTCCTTTTCAGACTTCTTAACAGTTGTGGATAAAGCATTAGCCGTTATAGAAAAATCA
CAATTCTATAGCTATAAACCTAGTGTTTTTGTTCTCAAAGCTAAATATGAACTTCTGCATAAGGGAAATAAGAAAAAGGC
TGCAGAGAATTACGATAAGGCCATAATGTTTGCTTCCGTTTTAGAAGACTCGGTTTTAGAAGAAAGTATAAGAGCAGGGA
AAGCGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GG23

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius strain HSISS4

97.324

100

0.973
  comR Streptococcus salivarius SK126

97.324

100

0.973
  comR Streptococcus thermophilus LMG 18311

93.311

100

0.933
  comR Streptococcus thermophilus LMD-9

92.642

100

0.926
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

41.806

100

0.418

Multiple sequence alignment