Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   A6J31_RS10770 Genome accession   NZ_CP020431
Coordinates   2084414..2086510 (+) Length   698 a.a.
NCBI ID   WP_080611183.1    Uniprot ID   A0A1V0GG19
Organism   Streptococcus sp. FDAARGOS_192     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2079414..2091510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS10745 (A6J31_10685) trkA 2079504..2080853 (-) 1350 WP_014633874.1 Trk system potassium transporter TrkA -
  A6J31_RS10750 (A6J31_10690) - 2081131..2081640 (+) 510 WP_070655612.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  A6J31_RS10755 (A6J31_10695) - 2081949..2082506 (+) 558 WP_070849311.1 ECF transporter S component -
  A6J31_RS10760 (A6J31_10700) - 2082509..2083159 (+) 651 WP_073687416.1 phosphatase PAP2 family protein -
  A6J31_RS10765 (A6J31_10705) comR 2083340..2084239 (+) 900 WP_073687415.1 helix-turn-helix transcriptional regulator Regulator
  A6J31_RS10770 (A6J31_10710) comA 2084414..2086510 (+) 2097 WP_080611183.1 peptide cleavage/export ABC transporter Regulator
  A6J31_RS10775 (A6J31_10715) - 2086635..2086967 (+) 333 WP_014633880.1 DUF805 domain-containing protein -
  A6J31_RS10780 (A6J31_10720) - 2087019..2088410 (-) 1392 WP_048790673.1 DUF4153 domain-containing protein -
  A6J31_RS10785 (A6J31_10725) - 2088817..2089332 (+) 516 WP_048790674.1 AmiS/UreI family transporter -
  A6J31_RS10790 (A6J31_10730) - 2089357..2089659 (+) 303 WP_002886558.1 urease subunit gamma -
  A6J31_RS10795 (A6J31_10735) - 2089671..2089982 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78409.36 Da        Isoelectric Point: 9.0880

>NTDB_id=222914 A6J31_RS10770 WP_080611183.1 2084414..2086510(+) (comA) [Streptococcus sp. FDAARGOS_192]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGVETQAIRADLDLFKQESLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSQQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVGRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=222914 A6J31_RS10770 WP_080611183.1 2084414..2086510(+) (comA) [Streptococcus sp. FDAARGOS_192]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGCGTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAGCCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGATTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACTTACACTAAATACAAAGAAGATGTGCCTGGGCTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTAACCATGATTTCGCTAGGCCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGGAATTACTTGTCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCTTACCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATAACGTCACGTTT
TGGCGATGCTAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTTTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTGCCTCTTTATGTTTTAATCATT
TTGGCCTTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAAAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACACAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTATGGTATGGGGCACAATTGGTCATGGAAGGACAGCTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCTAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCCTTTAAACAACTTGCTCTT
AAGGGTGTTAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGGGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACGACCTTGGCTAAAATGTTGTCGGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTAGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACAGGCACTATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAAGATGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGAGCCCTCTTGTCCCAGCAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTTCGTCAACATGTCGGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCGGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(494-640)

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter transmembrane region (ABC_membrane)

(167-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GG19

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.98

98.997

0.534
  comA Streptococcus gordonii str. Challis substr. CH1

53.305

99.713

0.532
  comA Streptococcus mitis NCTC 12261

53.546

98.997

0.53
  comA Streptococcus pneumoniae Rx1

53.401

98.997

0.529
  comA Streptococcus pneumoniae D39

53.401

98.997

0.529
  comA Streptococcus pneumoniae R6

53.401

98.997

0.529
  comA Streptococcus pneumoniae TIGR4

53.256

98.997

0.527
  comA/nlmT Streptococcus mutans UA159

50.435

98.854

0.499

Multiple sequence alignment