Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   C2H97_RS18260 Genome accession   NZ_CP026038
Coordinates   3487135..3489018 (+) Length   627 a.a.
NCBI ID   WP_120028099.1    Uniprot ID   -
Organism   Bacillus subtilis PY79 strain PK1_3     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3482135..3494018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H97_RS18245 (C2H97_18260) ymcA 3483172..3483603 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  C2H97_RS18250 (C2H97_18265) cotE 3483865..3484410 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  C2H97_RS18255 (C2H97_18270) hexA 3484543..3487119 (+) 2577 WP_120028098.1 DNA mismatch repair protein MutS Machinery gene
  C2H97_RS18260 (C2H97_18275) hexB 3487135..3489018 (+) 1884 WP_120028099.1 DNA mismatch repair endonuclease MutL Machinery gene
  C2H97_RS18265 (C2H97_18280) ymzD 3489416..3489871 (-) 456 WP_015252068.1 regulatory YrvL family protein -
  C2H97_RS18270 (C2H97_18285) - 3490026..3490583 (-) 558 WP_038428985.1 hypothetical protein -
  C2H97_RS18275 (C2H97_18290) pksA 3490704..3491321 (+) 618 WP_003231827.1 TetR/AcrR family transcriptional regulator -
  C2H97_RS18280 (C2H97_18295) pksB 3491511..3492188 (+) 678 WP_003231824.1 MBL fold metallo-hydrolase -
  C2H97_RS18285 (C2H97_18300) - 3492298..3492564 (+) 267 WP_120028100.1 hypothetical protein -
  C2H97_RS18290 (C2H97_18305) fabD 3492561..3493427 (+) 867 WP_038428987.1 ACP S-malonyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70521.43 Da        Isoelectric Point: 5.9976

>NTDB_id=222879 C2H97_RS18260 WP_120028099.1 3487135..3489018(+) (hexB) [Bacillus subtilis PY79 strain PK1_3]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPERKVPEKAHAPSYSPMKLSSVVKEPVDTEEELPPHQFDAPPI
VDQEQTLEVSDVSAKEPDTFEQECHEGQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=222879 C2H97_RS18260 WP_120028099.1 3487135..3489018(+) (hexB) [Bacillus subtilis PY79 strain PK1_3]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCTGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGACGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCTCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCAGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAATGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTTCCGAAAAAATCGGCACCTGTTATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAGAAAAGTACCGGAAAAAGCGCATGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATACGGAGGAAGAATTGCCTCCTCACCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGCGAAAGAGCCAGATACATTTGAGCAGGAATGCCATGAGGG
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCCGCGATTATGATGAGCTGTAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

MutL C terminal dimerisation domain (MutL_C)

(442-583)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.595

100

0.47

Multiple sequence alignment