Detailed information NTG0222878

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: C2H97_RS18255
• Genome accession: NZ_CP026038
• Coordinates: 3484543..3487119 (+)
• Length: 858 a.a.
• NCBI ID: WP_120028098.1
• Uniprot ID: -
• Organism: Bacillus subtilis PY79 strain PK1_3
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 3479543..3492119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2H97_RS18235 (C2H97_18250)	kbl	3480315..3481493 (+)	1179	WP_015715903.1	glycine C-acetyltransferase	-
C2H97_RS18240 (C2H97_18255)	miaB	3481641..3483170 (+)	1530	WP_049140040.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
C2H97_RS18245 (C2H97_18260)	ymcA	3483172..3483603 (+)	432	WP_003231834.1	regulatory iron-sulfur-containing complex subunit RicA	Regulator
C2H97_RS18250 (C2H97_18265)	cotE	3483865..3484410 (+)	546	WP_003231833.1	outer spore coat protein CotE	-
C2H97_RS18255 (C2H97_18270)	hexA	3484543..3487119 (+)	2577	WP_120028098.1	DNA mismatch repair protein MutS	Machinery gene
C2H97_RS18260 (C2H97_18275)	hexB	3487135..3489018 (+)	1884	WP_120028099.1	DNA mismatch repair endonuclease MutL	Machinery gene
C2H97_RS18265 (C2H97_18280)	ymzD	3489416..3489871 (-)	456	WP_015252068.1	regulatory YrvL family protein	-
C2H97_RS18270 (C2H97_18285)	-	3490026..3490583 (-)	558	WP_038428985.1	hypothetical protein	-
C2H97_RS18275 (C2H97_18290)	pksA	3490704..3491321 (+)	618	WP_003231827.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 97587.78 Da
• Isoelectric Point: 5.3551

>NTDB_id=222878 C2H97_RS18255 WP_120028098.1 3484543..3487119(+) (hexA) [Bacillus subtilis PY79 strain PK1_3]
MAGYTPMIQQYLKIKAEHQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGAAEKIPMCGVPYHSASAYIEQLIKK
GYKVAICEQTEDPKAAKGVVKREVVQLITPGTVMDGKGIHESENNFIASVSACSNGYGLALSDLTTGENLAVLIERLEDV
ISEIYSVGAREIVVSGSLDADTVAQLRERCGATISIEDGETDEHVTIIEHLNNEDITKTFLRLYTYLKRTQKRSLDHLQP
VQVYELEEAMKIDLYSKRNLELTETIRSKNKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRVNQIEERQEMVETLMSHFF
EREDLRERLKEVYDLERLAGRVAFGNVNARDLIQLKESLKQVPGIKQLVASLAHDKAKERAKRIDPCGDVLELLEEALYE
NPPLSVKEGNLIKDGYNQKLDEYRDASRNGKDWIARLEQQEREYTGIRSLKVGFNKVFGYYIEVTKANLHLLEEGRYERK
QTLTNAERYITPELKEKEALILEAENNICELEYELFTELREKVKQYIPRLQLLAKQMSELDALQCFATISENRHYTKPEF
SKDEVKVIEGRHPVVEKVMDSQEYVPNNCMMGDNRQMLLITGPNMSGKSTYMRQIALISIMAQIGCFVPAKKAVLPIFDQ
IFTRIGAADDLISGQSTFMVEMLEAKNAIVNATKNSLILFDEIGRGTSTYDGMALAQAIIEYVHDHIGAKTLFSTHYHEL
TVLEDKLPQLKNVHVRAEEYNGTVVFLHQIKEGAADKSYGIHVAQLAELPGDLIARAQDILKELEHSGNKPEVPVQKPQV
KEEPAQLSFFDEAEKPAETPKLSKKEKQVIDAFKSLNILDMTPLEAMNEMYKLQKKLH

Nucleotide

• Length: 2577 bp

>NTDB_id=222878 C2H97_RS18255 WP_120028098.1 3484543..3487119(+) (hexA) [Bacillus subtilis PY79 strain PK1_3]
ATGGCCGGTTATACGCCTATGATACAGCAATATTTAAAAATAAAGGCAGAGCACCAGGATGCCTTTTTATTTTTTCGCCT
GGGTGATTTTTATGAAATGTTTTTTGAGGACGCCAAAAAAGCGTCACAAGAGCTGGAAATTACGTTAACGAGCAGAGACG
GCGGTGCGGCTGAAAAAATACCGATGTGCGGTGTGCCGTATCATTCTGCTTCCGCGTATATCGAACAGCTTATTAAAAAA
GGATACAAAGTGGCGATCTGTGAACAGACGGAAGATCCGAAAGCCGCAAAGGGCGTTGTGAAAAGAGAAGTAGTTCAGCT
GATTACGCCCGGAACTGTAATGGACGGCAAAGGCATCCATGAATCGGAAAATAACTTTATCGCATCTGTTTCAGCCTGCT
CGAACGGATACGGACTTGCGCTGTCTGATTTAACAACGGGAGAAAATTTGGCTGTTTTGATTGAACGGCTTGAAGACGTC
ATATCAGAAATTTATTCAGTCGGCGCAAGGGAAATAGTGGTTTCAGGAAGCTTGGATGCCGATACAGTGGCACAGCTGAG
AGAGCGGTGCGGTGCAACGATTTCAATTGAAGACGGAGAAACAGACGAACACGTAACGATCATTGAGCACTTAAATAATG
AAGATATAACAAAAACATTTCTGCGCTTATATACGTATTTGAAAAGAACCCAAAAGCGCAGCCTTGATCATCTTCAGCCC
GTGCAGGTGTATGAGCTTGAGGAAGCGATGAAAATTGATTTGTACTCAAAGCGTAATCTGGAGCTGACCGAAACGATCCG
TTCAAAAAATAAAAAAGGCTCCCTTTTGTGGCTGCTGGATGAAACAAAAACGGCAATGGGAGGCCGGCTGCTTAAACAGT
GGATTGACCGGCCGCTTATCAGAGTCAATCAAATCGAAGAGCGCCAAGAAATGGTGGAAACATTGATGTCCCATTTCTTT
GAACGGGAAGATCTGCGTGAACGTTTAAAAGAAGTATATGACTTAGAACGCCTTGCCGGCCGCGTTGCATTCGGAAATGT
CAATGCCCGGGATTTGATTCAGCTGAAGGAATCGTTAAAGCAAGTTCCTGGCATCAAACAGCTGGTTGCTTCACTGGCTC
ATGACAAGGCCAAGGAACGTGCAAAGCGCATTGACCCTTGCGGGGATGTACTTGAACTGCTGGAAGAAGCGCTGTACGAA
AACCCTCCTTTATCGGTAAAAGAAGGGAACCTGATTAAAGATGGTTATAATCAAAAGCTTGATGAATATCGTGATGCAAG
CAGAAACGGAAAAGACTGGATTGCCCGCTTGGAACAGCAGGAGCGGGAATACACAGGCATTCGCTCTTTAAAGGTCGGCT
TTAATAAAGTTTTCGGTTATTACATTGAAGTGACTAAAGCAAACTTGCATTTGCTTGAGGAAGGGCGTTATGAGCGGAAG
CAGACGTTAACCAATGCAGAGCGCTACATTACACCTGAATTAAAAGAAAAAGAAGCGCTCATTTTAGAAGCGGAAAATAA
CATCTGTGAGCTGGAGTACGAGCTGTTTACTGAGCTCCGCGAGAAAGTGAAGCAGTATATTCCGCGGCTGCAGTTGCTTG
CAAAACAGATGAGCGAGCTGGACGCACTGCAATGCTTTGCGACAATCAGTGAAAATCGCCACTACACGAAACCGGAGTTC
TCTAAAGATGAAGTCAAAGTGATTGAAGGCAGACACCCGGTTGTTGAAAAAGTCATGGACAGCCAGGAATATGTCCCGAA
CAACTGTATGATGGGCGATAACAGACAAATGCTTCTCATTACAGGTCCAAACATGTCAGGGAAAAGCACGTATATGAGAC
AAATCGCGCTCATTTCCATTATGGCGCAAATCGGCTGCTTTGTACCCGCGAAAAAAGCGGTGCTCCCGATTTTCGATCAA
ATTTTTACGCGAATCGGCGCTGCAGATGATTTGATTTCCGGACAAAGTACATTTATGGTAGAAATGCTTGAAGCGAAAAA
TGCGATTGTCAACGCGACGAAAAACAGCCTCATTCTGTTTGATGAAATCGGGCGGGGAACGTCCACTTATGACGGCATGG
CGCTGGCACAGGCGATTATTGAATATGTTCACGATCACATCGGCGCCAAGACGCTGTTCAGCACACACTATCACGAGCTG
ACCGTTCTTGAGGACAAGCTGCCCCAGCTGAAAAACGTTCATGTTCGCGCTGAAGAATATAACGGAACGGTTGTCTTTCT
TCATCAAATCAAAGAAGGTGCCGCTGATAAAAGCTATGGTATCCATGTAGCTCAGCTTGCCGAACTGCCGGGAGATCTGA
TTGCCCGCGCCCAAGATATTTTAAAAGAGCTTGAGCATTCAGGAAACAAACCGGAAGTGCCGGTGCAGAAACCTCAGGTG
AAAGAAGAGCCGGCACAGCTGTCCTTTTTTGACGAAGCGGAAAAGCCGGCTGAAACACCAAAGCTTTCAAAAAAAGAAAA
GCAAGTGATCGATGCTTTCAAATCACTTAATATACTGGATATGACACCGCTTGAAGCGATGAATGAAATGTACAAGCTGC
AAAAGAAATTACATTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (598-785)

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain II (MutS_II) (125-239)

• MutS domain I (MutS_I) (5-116)

• MutS domain III (MutS_III) (258-547)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	49.474	99.65	0.493
mutS	Pseudomonas stutzeri strain ATCC 17587	39.135	100	0.401