Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6J38_RS08065 Genome accession   NZ_CP020411
Coordinates   1630822..1632159 (+) Length   445 a.a.
NCBI ID   WP_005693728.1    Uniprot ID   -
Organism   Haemophilus influenzae strain FDAARGOS_199     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1625822..1637159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J38_RS08040 (A6J38_08035) - 1625887..1628481 (-) 2595 WP_005693721.1 penicillin-binding protein 1A -
  A6J38_RS08045 (A6J38_08040) comA 1628580..1629377 (+) 798 WP_005693722.1 competence protein A Machinery gene
  A6J38_RS08050 (A6J38_08045) comB 1629378..1629884 (+) 507 WP_005693724.1 competence protein ComB Machinery gene
  A6J38_RS08055 (A6J38_08050) comC 1629881..1630402 (+) 522 WP_005693726.1 competence protein ComC Machinery gene
  A6J38_RS08060 (A6J38_08055) comD 1630399..1630812 (+) 414 WP_005693727.1 pilus assembly protein PilP Machinery gene
  A6J38_RS08065 (A6J38_08060) comE 1630822..1632159 (+) 1338 WP_005693728.1 type IV pilus secretin PilQ family protein Machinery gene
  A6J38_RS08070 (A6J38_08065) - 1632171..1632857 (+) 687 WP_032828380.1 ComF family protein -
  A6J38_RS08075 (A6J38_08070) nfuA 1632933..1633529 (+) 597 WP_005693730.1 Fe-S biogenesis protein NfuA -
  A6J38_RS08080 (A6J38_08075) nudC 1633596..1634390 (+) 795 WP_005693731.1 NAD(+) diphosphatase -
  A6J38_RS08085 (A6J38_08080) - 1634426..1635016 (+) 591 WP_005693732.1 YjaG family protein -
  A6J38_RS08090 (A6J38_08085) - 1635156..1635428 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49208.48 Da        Isoelectric Point: 7.4786

>NTDB_id=222409 A6J38_RS08065 WP_005693728.1 1630822..1632159(+) (comE) [Haemophilus influenzae strain FDAARGOS_199]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVIGDILENKISLKLNNIDMPRLLQ
IIAKSKHLTLNKDDGIYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPAGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSEGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=222409 A6J38_RS08065 WP_005693728.1 1630822..1632159(+) (comE) [Haemophilus influenzae strain FDAARGOS_199]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATTGGAGATATATTGGAAAACAAGATCTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTACAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGATTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAGGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTGAGTCACACGGTAAAACTCCATTTTGCTAAAGCTTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGCTCTTTGCTTTCTCCCGCTGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCCAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGCCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCGGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAACAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGATACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTAGTGATTTTCGTCACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGAGGGTAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

100

100

1
  comE Haemophilus influenzae 86-028NP

97.528

100

0.975
  comE Glaesserella parasuis strain SC1401

52.941

95.506

0.506
  pilQ Vibrio campbellii strain DS40M4

42.482

94.157

0.4
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.748

92.584

0.387
  pilQ Vibrio cholerae strain A1552

41.748

92.584

0.387

Multiple sequence alignment