Detailed information NTG0221661

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: BLMD_RS18545
• Genome accession: NZ_CP020352
• Coordinates: 3676914..3677510 (+)
• Length: 198 a.a.
• NCBI ID: WP_003185550.1
• Uniprot ID: A0A1J6GJE1
• Organism: Bacillus paralicheniformis strain MDJK30
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3671914..3682510

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BLMD_RS18525 (BLMD_18525)	-	3672874..3674319 (+)	1446	WP_023856345.1	glycoside hydrolase family 68 protein	-
BLMD_RS18530 (BLMD_18530)	-	3674399..3675946 (+)	1548	WP_039073036.1	glycoside hydrolase family 32 protein	-
BLMD_RS22225	-	3676011..3676163 (-)	153	WP_023856347.1	hypothetical protein	-
BLMD_RS22435	-	3676511..3676630 (-)	120	WP_075212739.1	NINE protein	-
BLMD_RS18545 (BLMD_18545)	clpP	3676914..3677510 (+)	597	WP_003185550.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
BLMD_RS18550 (BLMD_18550)	-	3677585..3678160 (-)	576	WP_023856348.1	TIGR00730 family Rossman fold protein	-
BLMD_RS18555 (BLMD_18555)	-	3678271..3678606 (+)	336	WP_020453047.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
BLMD_RS18560 (BLMD_18560)	-	3678593..3679570 (+)	978	WP_020453048.1	HD domain-containing protein	-
BLMD_RS18565 (BLMD_18565)	-	3679618..3681237 (-)	1620	WP_020453049.1	SulP family inorganic anion transporter	-
BLMD_RS18570 (BLMD_18570)	-	3681238..3681837 (-)	600	WP_020453050.1	beta-class carbonic anhydrase	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21803.99 Da
• Isoelectric Point: 4.7982

>NTDB_id=221661 BLMD_RS18545 WP_003185550.1 3676914..3677510(+) (clpP) [Bacillus paralicheniformis strain MDJK30]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPQVSTICTGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILSLRDKLNKILAERTGQ
PLEVIERDTDRDNFKTAEEAKEYGLIDKVLTRNIDAQK

Nucleotide

• Length: 597 bp

>NTDB_id=221661 BLMD_RS18545 WP_003185550.1 3676914..3677510(+) (clpP) [Bacillus paralicheniformis strain MDJK30]
ATGAATTTAATACCTACAGTCATTGAACAGACGAACCGCGGGGAAAGAGCGTATGACATTTACTCACGCTTGTTGAAAGA
CCGTATCATTATGCTGGGATCAGCAATCGATGACAATGTTGCGAACTCCATCGTATCTCAGCTTCTATTCCTTGAAGCCG
AAGATCCAGAAAAAGATATCAGCATCTATATTAACAGCCCTGGCGGCTCTATCACAGCCGGCATGGCGATTTATGACACC
ATGCAGTTCATTAAACCTCAAGTCTCTACGATTTGTACGGGAATGGCGGCATCTATGGGTGCGTTCCTTCTCGCAGCCGG
CGAGAAAGGGAAGCGCTACGCTCTTCCAAACAGTGAAGTCATGATCCACCAGCCGCTTGGCGGAGCGCAAGGTCAGGCAA
CAGAAATCGAAATTGCCGCGAAGCGCATTCTTTCATTGCGTGACAAACTGAACAAAATTCTTGCAGAGCGCACTGGACAA
CCGCTTGAAGTGATCGAGCGCGATACAGACCGTGACAACTTCAAAACGGCTGAAGAAGCAAAAGAATACGGCCTGATTGA
TAAAGTGCTCACACGCAATATCGACGCACAGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A1J6GJE1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	92.386	99.495	0.919
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.229	96.97	0.662
clpP	Streptococcus thermophilus LMG 18311	58.031	97.475	0.566
clpP	Streptococcus thermophilus LMD-9	58.031	97.475	0.566
clpP	Lactococcus lactis subsp. cremoris KW2	56.995	97.475	0.556
clpP	Streptococcus pneumoniae Rx1	56.995	97.475	0.556
clpP	Streptococcus pneumoniae D39	56.995	97.475	0.556
clpP	Streptococcus pneumoniae R6	56.995	97.475	0.556
clpP	Streptococcus pneumoniae TIGR4	56.995	97.475	0.556
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Streptococcus mutans UA159	54.639	97.98	0.535
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.922	97.475	0.535