Detailed information NTG0220329

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: BS21228_RS08645
• Genome accession: NZ_CP020023
• Coordinates: 1583751..1584344 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain ATCC 21228
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1578751..1589344

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BS21228_RS08610 (BS21228_08565)	-	1579479..1579694 (+)	216	WP_033881551.1	helix-turn-helix transcriptional regulator	-
BS21228_RS08615 (BS21228_08570)	-	1579896..1580231 (-)	336	WP_031601018.1	hypothetical protein	-
BS21228_RS08620 (BS21228_08575)	-	1580820..1581053 (+)	234	WP_033881293.1	helix-turn-helix domain-containing protein	-
BS21228_RS08625 (BS21228_08580)	-	1581113..1581295 (+)	183	WP_033881294.1	hypothetical protein	-
BS21228_RS08630 (BS21228_08585)	-	1581326..1582057 (-)	732	WP_041516560.1	helix-turn-helix domain-containing protein	-
BS21228_RS08635 (BS21228_08590)	-	1582216..1583205 (-)	990	WP_014480981.1	tyrosine-type recombinase/integrase	-
BS21228_RS08645 (BS21228_08600)	clpP	1583751..1584344 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
BS21228_RS08650 (BS21228_08605)	pgmB	1584407..1585081 (-)	675	WP_014480982.1	beta-phosphoglucomutase	-
BS21228_RS08655 (BS21228_08610)	malL	1585078..1586763 (-)	1686	WP_033881298.1	oligo-1,6-glucosidase	-
BS21228_RS08660 (BS21228_08615)	mdxK	1586756..1589029 (-)	2274	WP_014480985.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=220329 BS21228_RS08645 WP_003228214.1 1583751..1584344(+) (clpP) [Bacillus subtilis strain ATCC 21228]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=220329 BS21228_RS08645 WP_003228214.1 1583751..1584344(+) (clpP) [Bacillus subtilis strain ATCC 21228]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCATCAATGGGCGCTTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAACTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538