Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CXR04_RS18750 Genome accession   NZ_CP025407
Coordinates   4307286..4307972 (+) Length   228 a.a.
NCBI ID   WP_101423531.1    Uniprot ID   -
Organism   Streptomyces sp. CMB-StM0423     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4302286..4312972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXR04_RS18725 (CXR04_18725) - 4302733..4303836 (-) 1104 WP_101423526.1 ionic transporter y4hA -
  CXR04_RS18730 (CXR04_18730) - 4303975..4304916 (-) 942 WP_101423527.1 AraC family transcriptional regulator -
  CXR04_RS18735 (CXR04_18735) - 4304998..4305828 (+) 831 WP_101423528.1 NAD(P)H-binding protein -
  CXR04_RS18740 (CXR04_18740) - 4305821..4306336 (+) 516 WP_101423529.1 DUF1772 domain-containing protein -
  CXR04_RS18745 (CXR04_18745) - 4306607..4307155 (-) 549 WP_101423530.1 PepSY domain-containing protein -
  CXR04_RS18750 (CXR04_18750) ciaR 4307286..4307972 (+) 687 WP_101423531.1 response regulator transcription factor Regulator
  CXR04_RS18755 (CXR04_18755) - 4307965..4309656 (+) 1692 WP_101423532.1 HAMP domain-containing sensor histidine kinase -
  CXR04_RS18760 (CXR04_18760) - 4309893..4311467 (-) 1575 WP_101423533.1 aminopeptidase P family protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24629.04 Da        Isoelectric Point: 5.0088

>NTDB_id=218767 CXR04_RS18750 WP_101423531.1 4307286..4307972(+) (ciaR) [Streptomyces sp. CMB-StM0423]
MRLLIVEDERRLATSLARGLAAEGFAVDVVHDGVEGLHRATETDYDLIVLDIMLPGLNGYRVCAALRAAGDETPILMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLLARVRALLRRRGRTAAPVLRVGALAVDPAARRVHVGDTEVTLTTKEFAVLEV
LAQRAGEVVAKSEILDHAWDFAYDGDPNIVEVYVSALRRKLGARTIQTVRGAGYRLADPDATGGSARA

Nucleotide


Download         Length: 687 bp        

>NTDB_id=218767 CXR04_RS18750 WP_101423531.1 4307286..4307972(+) (ciaR) [Streptomyces sp. CMB-StM0423]
ATGCGACTGCTGATCGTCGAGGACGAGCGACGCCTCGCCACCTCCCTCGCCCGCGGGCTCGCCGCCGAGGGCTTCGCCGT
GGACGTCGTCCACGACGGCGTCGAGGGCCTCCACCGGGCCACCGAGACCGACTACGACCTCATCGTCCTCGACATCATGC
TCCCCGGCCTGAACGGCTACCGCGTCTGCGCCGCCCTCCGCGCCGCAGGCGACGAGACCCCGATCCTCATGCTCACCGCC
AAAGACGGCGAATACGACGAAGCCGAGGGCCTCGACACCGGCGCCGACGACTACCTCACCAAGCCCTTCAGCTACGTCGT
CCTCCTCGCCCGCGTACGCGCCCTCCTGCGCCGCCGCGGCCGCACCGCCGCCCCCGTCCTGCGCGTCGGCGCCCTCGCCG
TCGACCCCGCCGCGCGCCGGGTCCACGTCGGGGACACCGAGGTGACGCTGACGACCAAGGAGTTCGCGGTCCTCGAAGTG
CTCGCCCAGCGCGCCGGGGAGGTCGTCGCCAAGTCCGAGATCCTCGACCACGCCTGGGACTTCGCGTACGACGGCGACCC
CAACATCGTCGAGGTCTACGTCAGCGCCCTGCGCCGCAAACTCGGCGCCCGCACCATCCAGACCGTACGCGGCGCCGGCT
ACCGCCTCGCCGACCCCGACGCAACCGGCGGCAGCGCCCGTGCGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

43.111

98.684

0.425
  ciaR Streptococcus pneumoniae Rx1

42.152

97.807

0.412
  ciaR Streptococcus pneumoniae D39

42.152

97.807

0.412
  ciaR Streptococcus pneumoniae R6

42.152

97.807

0.412
  ciaR Streptococcus pneumoniae TIGR4

42.152

97.807

0.412
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.081

96.93

0.408
  covR Streptococcus salivarius strain HSISS4

41.441

97.368

0.404
  vicR Streptococcus mutans UA159

38.889

100

0.399
  micA Streptococcus pneumoniae Cp1015

36.245

100

0.364