Detailed information NTG0217516

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ADP71_RS12530
• Genome accession: NZ_CP019644
• Coordinates: 2546403..2547500 (-)
• Length: 365 a.a.
• NCBI ID: WP_104932333.1
• Uniprot ID: A0A2L0PQP0
• Organism: Vitreoscilla sp. C1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2541403..2552500

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ADP71_RS12515 (ADP71_32770)	rbsD	2542834..2543223 (-)	390	WP_019959257.1	D-ribose pyranase	-
ADP71_RS12520 (ADP71_32780)	topA	2543511..2545829 (-)	2319	WP_171461193.1	type I DNA topoisomerase	-
ADP71_RS12525 (ADP71_32790)	-	2545928..2546386 (-)	459	WP_104932332.1	DUF494 domain-containing protein	-
ADP71_RS12530 (ADP71_32800)	dprA	2546403..2547500 (-)	1098	WP_104932333.1	DNA-processing protein DprA	Machinery gene
ADP71_RS12535 (ADP71_32810)	-	2547555..2548820 (-)	1266	WP_171461194.1	LysM peptidoglycan-binding domain-containing protein	-
ADP71_RS12540 (ADP71_32830)	def	2548989..2549486 (+)	498	WP_019959262.1	peptide deformylase	-
ADP71_RS12545 (ADP71_32840)	fmt	2549487..2550419 (+)	933	WP_171461195.1	methionyl-tRNA formyltransferase	-
ADP71_RS12550 (ADP71_32850)	rsmB	2550416..2551672 (+)	1257	WP_171461196.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
ADP71_RS12555 (ADP71_32880)	-	2551638..2552225 (+)	588	WP_257793067.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 365 a.a.
• Molecular weight: 39591.41 Da
• Isoelectric Point: 6.4492

>NTDB_id=217516 ADP71_RS12530 WP_104932333.1 2546403..2547500(-) (dprA) [Vitreoscilla sp. C1]
MNDAHRLAYLELALTPYVGPMTLLKILQYLDYPADIWQTPISALSNLAKPKAIQAIQQRQGKQALQDALIWESEHANNHL
LSLLDDDYPLNLAQIDSPPPLLFAKGDLSLLHQPSIAIIGSRHATAQGLQNAHRFAADLSQHNMAIVSGFAAGIDTAAHQ
GCIQVNGATIAVLGTGIDRVYPAANRQLAHQICEKGLLLSEFALGTPPVAQNFPRRNRIIAALSQAILVVEAAVESGSLI
TARLGLEMNKEVMAIPGSIHNPHSKGCHALIKQGAKLIESTQDILEECILLPQLHKNTHFEPKANTDNHPNPSPLLQAMG
FDPIHPDQLVDKLGSSLTDVYAELLELELQGQIAALTGGRYQRIH

Nucleotide

• Length: 1098 bp

>NTDB_id=217516 ADP71_RS12530 WP_104932333.1 2546403..2547500(-) (dprA) [Vitreoscilla sp. C1]
ATGAACGATGCCCACCGCTTGGCTTATCTTGAATTGGCCCTCACGCCTTATGTCGGTCCCATGACCCTATTAAAAATATT
ACAATATTTGGATTATCCTGCTGACATTTGGCAAACACCAATCTCTGCACTTTCCAACTTAGCCAAACCCAAAGCCATTC
AAGCCATACAACAACGTCAAGGCAAACAAGCTTTACAGGACGCTTTAATATGGGAAAGCGAACATGCAAACAACCATTTA
TTGTCTTTACTAGACGATGATTATCCATTAAATTTAGCACAAATTGACTCGCCACCACCGTTATTGTTCGCCAAAGGCGA
TTTATCCTTATTACATCAACCTAGCATAGCGATTATCGGTAGCCGCCACGCGACAGCCCAAGGCTTACAAAATGCTCACA
GATTTGCGGCAGATTTAAGCCAACACAATATGGCGATTGTTTCTGGATTTGCCGCAGGCATCGACACCGCAGCCCATCAA
GGCTGTATTCAAGTAAATGGTGCCACTATCGCTGTTTTGGGAACAGGCATAGACCGCGTTTATCCTGCGGCCAATCGCCA
ATTGGCACATCAAATTTGTGAAAAAGGCTTATTGCTGTCAGAATTCGCCCTTGGAACACCACCTGTTGCGCAAAACTTCC
CAAGACGCAACCGCATCATTGCAGCTTTGTCGCAAGCGATTTTGGTGGTTGAAGCGGCTGTGGAATCAGGATCTTTAATT
ACAGCCCGCTTAGGATTGGAAATGAACAAAGAAGTGATGGCCATACCCGGCTCAATTCACAATCCTCATAGCAAAGGCTG
TCATGCGTTGATCAAACAAGGCGCCAAGCTCATTGAATCCACTCAAGATATTTTGGAAGAATGTATCCTTTTGCCGCAGC
TGCACAAAAATACCCATTTTGAGCCAAAAGCCAATACAGACAACCATCCAAATCCATCACCGCTCTTGCAAGCCATGGGT
TTTGACCCCATACATCCTGACCAATTGGTCGATAAACTTGGCAGCAGCCTTACAGATGTGTATGCTGAATTATTGGAATT
AGAGCTACAAGGTCAAATTGCAGCACTCACAGGTGGTCGTTACCAACGAATTCATTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (76-279)

• DprA winged helix domain (DprA_WH) (311-359)

3D structure

• AlphaFold DB: A0A2L0PQP0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	47.75	100	0.523
dprA	Neisseria meningitidis MC58	47.75	100	0.523
dprA	Neisseria gonorrhoeae MS11	47.487	100	0.518
dprA	Neisseria gonorrhoeae strain FA1090	46.985	100	0.512
dprA	Legionella pneumophila strain ERS1305867	44.286	95.89	0.425
dprA	Vibrio campbellii strain DS40M4	42.192	100	0.422
dprA	Vibrio cholerae strain A1552	39.892	100	0.405