Detailed information NTG0217366

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: BZ167_RS12865
• Genome accession: NZ_CP019626
• Coordinates: 2652539..2653135 (-)
• Length: 198 a.a.
• NCBI ID: WP_003151513.1
• Uniprot ID: I2CAH7
• Organism: Bacillus sp. 275
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2647539..2658135

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZ167_RS12840 (BZ167_12890)	-	2647657..2647977 (-)	321	WP_003151506.1	MazG-like family protein	-
BZ167_RS12845 (BZ167_12895)	-	2648093..2648668 (+)	576	WP_015387658.1	TIGR00730 family Rossman fold protein	-
BZ167_RS12850 (BZ167_12900)	-	2648911..2650287 (-)	1377	WP_015240656.1	MFS transporter	-
BZ167_RS12855 (BZ167_12905)	-	2650331..2651461 (-)	1131	WP_077392098.1	PrpF domain-containing protein	-
BZ167_RS12860 (BZ167_12910)	-	2651635..2652495 (+)	861	WP_061860902.1	LysR family transcriptional regulator	-
BZ167_RS12865 (BZ167_12915)	clpP	2652539..2653135 (-)	597	WP_003151513.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
BZ167_RS12870 (BZ167_12920)	-	2653383..2654357 (-)	975	WP_061860901.1	LacI family DNA-binding transcriptional regulator	-
BZ167_RS12875 (BZ167_12925)	-	2654748..2655980 (+)	1233	WP_061860900.1	MFS transporter	-
BZ167_RS12880 (BZ167_12930)	-	2655995..2657464 (+)	1470	WP_061860899.1	glycoside hydrolase family 32 protein	-
BZ167_RS12890 (BZ167_12940)	-	2657816..2658127 (-)	312	WP_015418282.1	hypothetical protein	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21831.06 Da
• Isoelectric Point: 4.6982

>NTDB_id=217366 BZ167_RS12865 WP_003151513.1 2652539..2653135(-) (clpP) [Bacillus sp. 275]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSADEALEYGLIDKVLTRNTEDQK

Nucleotide

• Length: 597 bp

>NTDB_id=217366 BZ167_RS12865 WP_003151513.1 2652539..2653135(-) (clpP) [Bacillus sp. 275]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCTTATGACATTTACTCCCGTCTTTTGAAGGA
CCGTATTATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCCTTGAAGCGG
AAGACCCTGAAAAAGATATTTCTATTTACATTAACAGCCCTGGCGGATCAATCACTGCCGGCATGGCAATCTATGATACA
ATGCAGTTCATTAAACCGAAAGTATCCACGATCTGCATCGGTATGGCCGCTTCTATGGGAGCATTTTTACTTGCAGCCGG
AGAAAAAGGCAAACGTTACGCGCTTCCTAACAGTGAAGTTATGATTCACCAGCCGCTTGGCGGAGCGCAAGGACAGGCGA
CAGAAATTGAAATCGCGGCAAAACGCATTCTTTTGCTTCGCGACAAATTAAACAAAGTGCTTGCTGAACGTACCGGCCAG
CCGCTTGAAGTCATTGAGCGCGATACAGACCGCGACAACTTCAAATCAGCTGATGAAGCCTTAGAATACGGCTTAATCGA
TAAAGTGCTGACACGCAATACAGAAGACCAGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: I2CAH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	95.96	100	0.96
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.586	96.465	0.662
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Streptococcus pneumoniae D39	57.216	97.98	0.561
clpP	Streptococcus pneumoniae Rx1	57.216	97.98	0.561
clpP	Streptococcus pneumoniae R6	57.216	97.98	0.561
clpP	Streptococcus pneumoniae TIGR4	57.216	97.98	0.561
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	97.98	0.556
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.639	97.98	0.535
clpP	Streptococcus mutans UA159	54.639	97.98	0.535