Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   BWR56_RS02940 Genome accession   NZ_CP019562
Coordinates   616076..616666 (+) Length   196 a.a.
NCBI ID   WP_000613467.1    Uniprot ID   A0AAX0N3L0
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 616076..625647 616076..616666 within 0


Gene organization within MGE regions


Location: 616076..625647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS02940 (BWR56_0579) clpP 616076..616666 (+) 591 WP_000613467.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  BWR56_RS02945 (BWR56_0580) - 616745..617014 (+) 270 WP_000462108.1 YlbG family protein -
  BWR56_RS02950 (BWR56_0581) - 617103..618263 (+) 1161 WP_000726128.1 ABC transporter substrate-binding protein -
  BWR56_RS02955 (BWR56_0582) - 618383..619252 (+) 870 WP_000941413.1 branched-chain amino acid ABC transporter permease -
  BWR56_RS02960 (BWR56_0583) - 619256..620212 (+) 957 WP_076984443.1 branched-chain amino acid ABC transporter permease -
  BWR56_RS02965 (BWR56_0584) - 620212..620976 (+) 765 WP_001186018.1 ABC transporter ATP-binding protein -
  BWR56_RS02970 (BWR56_0585) - 620976..621686 (+) 711 WP_000062204.1 ABC transporter ATP-binding protein -
  BWR56_RS02975 (BWR56_0586) - 622156..622812 (+) 657 WP_000268643.1 CBS domain-containing protein -
  BWR56_RS02985 (BWR56_0587) prfB 622923..624018 (+) 1096 WP_155760976.1 peptide chain release factor 2 -
  BWR56_RS02990 (BWR56_0588) ftsE 624036..624728 (+) 693 WP_000022275.1 cell division ATP-binding protein FtsE -
  BWR56_RS02995 (BWR56_0589) ftsX 624721..625647 (+) 927 WP_000625556.1 permease-like cell division protein FtsX -

Sequence


Protein


Download         Length: 196 a.a.        Molecular weight: 21362.37 Da        Isoelectric Point: 4.4829

>NTDB_id=216313 BWR56_RS02940 WP_000613467.1 616076..616666(+) (clpP) [Streptococcus oralis strain S.MIT/ORALIS-351]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGK
SVEQIHADAERDYWMSAQETLEYGFIDEIMANNSLS

Nucleotide


Download         Length: 591 bp        

>NTDB_id=216313 BWR56_RS02940 WP_000613467.1 616076..616666(+) (clpP) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGACATTTACTCTCGTCTTCTGAAAGACCGCAT
CATCATGCTAACAGGTCCAGTTGAAGACAACATGGCCAACTCTGTTATCGCCCAATTACTTTTCTTGGATGCCCAAGACA
GCACAAAAGATATTTACCTTTATGTCAACACACCTGGAGGCTCTGTGTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACAATCGTTATGGGGATGGCTGCATCCATGGGGACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAGA
CAGATATGGCAATCGCTGCAGAGCACTTGCTTAAAACTCGTAAGACTTTGGAGCAAATCCTTGCAGATAACTCTGGTAAA
TCAGTCGAGCAAATTCATGCTGACGCTGAACGTGATTACTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCTAATAATTCTTTAAGCTAA

Domains


Predicted by InterproScan.

(11-192)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

95.408

100

0.954

  clpP Streptococcus pneumoniae R6

95.408

100

0.954

  clpP Streptococcus pneumoniae TIGR4

95.408

100

0.954

  clpP Streptococcus pneumoniae D39

95.408

100

0.954

  clpP Streptococcus pyogenes JRS4

92.308

99.49

0.918

  clpP Streptococcus pyogenes MGAS315

92.308

99.49

0.918

  clpP Streptococcus thermophilus LMD-9

91.282

99.49

0.908

  clpP Streptococcus thermophilus LMG 18311

91.282

99.49

0.908

  clpP Streptococcus mutans UA159

88.718

99.49

0.883

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.692

99.49

0.872

  clpP Lactococcus lactis subsp. cremoris KW2

87.179

99.49

0.867

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.031

98.469

0.571

  clpP Bacillus subtilis subsp. subtilis str. 168

57.292

97.959

0.561


Multiple sequence alignment