Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   BZG42_RS02930 Genome accession   NZ_CP019557
Coordinates   590030..590734 (+) Length   234 a.a.
NCBI ID   WP_120171458.1    Uniprot ID   A0A2Z5TP69
Organism   Streptococcus sp. DAT741     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 585030..595734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS02910 (BZG42_02905) - 586843..587502 (-) 660 WP_155995672.1 amino acid ABC transporter permease -
  BZG42_RS02915 (BZG42_02910) - 587515..588213 (-) 699 WP_120171456.1 amino acid ABC transporter permease -
  BZG42_RS02920 (BZG42_02915) - 588228..589064 (-) 837 WP_120171457.1 transporter substrate-binding domain-containing protein -
  BZG42_RS02925 (BZG42_02920) - 589074..589835 (-) 762 WP_155995675.1 amino acid ABC transporter ATP-binding protein -
  BZG42_RS02930 (BZG42_02925) micA 590030..590734 (+) 705 WP_120171458.1 response regulator YycF Regulator
  BZG42_RS02935 (BZG42_02930) micB 590727..592076 (+) 1350 WP_024532081.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BZG42_RS02940 (BZG42_02935) vicX 592083..592886 (+) 804 WP_024532080.1 MBL fold metallo-hydrolase Regulator
  BZG42_RS02945 (BZG42_02940) pbp2b 593110..595185 (+) 2076 WP_024532079.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26830.85 Da        Isoelectric Point: 5.2517

>NTDB_id=216213 BZG42_RS02930 WP_120171458.1 590030..590734(+) (micA) [Streptococcus sp. DAT741]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALETFEKEFPDVVILDVMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSELTETQVNLSSTSTSELVIGDLVILPDAFVAKKHGRELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGNV

Nucleotide


Download         Length: 705 bp        

>NTDB_id=216213 BZG42_RS02930 WP_120171458.1 590030..590734(+) (micA) [Streptococcus sp. DAT741]
ATGAAAAAAATACTAATTGTAGATGATGAAAAACCAATCTCAGATATTATCAAATTTAATATGACCCGTGAAGGATATGA
AGTAGTGACAGCTTTTGACGGTCGTGAAGCACTGGAGACATTTGAGAAGGAATTTCCAGATGTTGTTATTTTGGATGTGA
TGTTGCCGGAGTTAGATGGACTAGAAGTGGCTCGAACAATCCGCAAGACTAGCAATGTTCCTATACTAATGCTATCAGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGTCTTGAACTTGGTGCGGATGACTATGTGACAAAGCCCTTCTCTAATCGTGA
ATTACAGGCGCGTGTCAAGGCTCTTCTTCGTCGCAGTGAATTGACAGAAACGCAAGTTAATCTTTCTTCCACAAGTACCT
CAGAGTTAGTTATTGGGGACTTAGTTATCTTGCCAGATGCTTTTGTGGCTAAAAAACATGGTAGGGAATTGGAGTTGACT
CATCGTGAGTTCGAATTGCTTCATCATCTAGCTAAGCATTTGGGTCAGGTGATGACTCGCGAGCATTTGCTGGAAACTGT
GTGGGGCTACGATTATTTTGGTGATGTTCGTACAGTGGATGTGACCATTCGCCGTCTGCGGGAGAAGATTGAAGATACGC
CAAGCAGACCTGAGTACATCCTGACCCGTCGAGGTGTAGGATATTTTATAAAGGGAAATGTTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TP69

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.769

100

0.808
  vicR Streptococcus mutans UA159

79.399

99.573

0.791
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.075

100

0.389

Multiple sequence alignment