Detailed information NTG0212212

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: BEI53_RS23190
• Genome accession: NZ_CP018935
• Coordinates: 4266078..4266659 (+)
• Length: 193 a.a.
• NCBI ID: WP_000991625.1
• Uniprot ID: A0A2A8KY00
• Organism: Bacillus cereus strain JEM-2
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4261078..4271659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BEI53_RS23165	-	4262200..4263567 (+)	1368	WP_001065248.1	lytic polysaccharide monooxygenase	-
BEI53_RS23170	-	4263698..4264132 (-)	435	WP_000555785.1	GNAT family N-acetyltransferase	-
BEI53_RS23175	rpiA	4264239..4264901 (-)	663	WP_001050001.1	ribose 5-phosphate isomerase A	-
BEI53_RS23180	-	4264906..4265226 (-)	321	WP_001125390.1	2Fe-2S iron-sulfur cluster-binding protein	-
BEI53_RS23185	-	4265370..4266056 (+)	687	WP_000337505.1	RNA polymerase subunit sigma-70	-
BEI53_RS23190	clpP	4266078..4266659 (+)	582	WP_000991625.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
BEI53_RS23195	-	4266705..4267562 (-)	858	WP_001227634.1	glycine betaine ABC transporter substrate-binding protein	-
BEI53_RS23200	-	4267734..4268939 (+)	1206	WP_000370609.1	quaternary amine ABC transporter ATP-binding protein	-
BEI53_RS23205	-	4268932..4269768 (+)	837	WP_001084757.1	ABC transporter permease	-
BEI53_RS23210	-	4270055..4270222 (+)	168	WP_002053336.1	hypothetical protein	-
BEI53_RS29865	-	4270409..4270504 (+)	96	Protein_4301	HIT family protein	-
BEI53_RS23215	-	4270488..4271312 (+)	825	WP_000557568.1	PP2C family serine/threonine-protein phosphatase	-

Sequence

Protein

• Length: 193 a.a.
• Molecular weight: 21178.42 Da
• Isoelectric Point: 5.0776

>NTDB_id=212212 BEI53_RS23190 WP_000991625.1 4266078..4266659(+) (clpP) [Bacillus cereus strain JEM-2]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide

• Length: 582 bp

>NTDB_id=212212 BEI53_RS23190 WP_000991625.1 4266078..4266659(+) (clpP) [Bacillus cereus strain JEM-2]
ATGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATACTCAAGGTTATTAAAAGA
CCGTATTGTTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCAGGTTTTGCTATATTAGATACG
ATGAATTTAATTAAACCAGACGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGCTATTATTATCAGG
TGCAAAAGGAAAACGGTTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCACAAGGGCAAGCGA
CGGAAATTGAAATCACAGCAAAAAGAATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (14-192)

3D structure

• AlphaFold DB: A0A2A8KY00

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	68.063	98.964	0.674
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	66.667	97.927	0.653
clpP	Streptococcus thermophilus LMD-9	54.688	99.482	0.544
clpP	Streptococcus pneumoniae Rx1	54.688	99.482	0.544
clpP	Streptococcus thermophilus LMG 18311	54.688	99.482	0.544
clpP	Streptococcus pneumoniae D39	54.688	99.482	0.544
clpP	Streptococcus pneumoniae R6	54.688	99.482	0.544
clpP	Streptococcus pneumoniae TIGR4	54.688	99.482	0.544
clpP	Streptococcus pyogenes MGAS315	55.556	97.927	0.544
clpP	Streptococcus pyogenes JRS4	55.556	97.927	0.544
clpP	Streptococcus mutans UA159	53.439	97.927	0.523
clpP	Lactococcus lactis subsp. cremoris KW2	51.852	97.927	0.508
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	49.735	97.927	0.487